Immune Architecture of Early Human Aortic Atherosclerosis Reveals Prominent T-Cell and Myeloid Compartments: Beyond Coronaries | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.jacbt…

Applying Spatial Transcriptomics to the Human Heart: A Practical Guide for Translational Studies | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.jacbt…

Left Ventricular Structural, Physiological, and Transcriptomic Abnormalities in a Novel Porcine Hypertrophic Cardiomyopathy Model | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.jacbt…

Cardiac Fibrosis as a Dynamic Therapeutic Target: Overcoming Translational Barriers to Antifibrotic Therapy | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.jacbt…

I’m honored and excited to serve as Chair of the Nash Family Department of Neuroscience at Mount Sinai! Grateful to follow in the footsteps of @PaulKenny and @EricNestler and build on their incredible legacy. Looking forward to what we’ll achieve together! #Neuroscience

Check out our review on modeling the exposome in murine cardiovascular disease! We need to expand holistic whole organism models to study lifestyle and environmental impacts on health to identify evolutionarily selected inter-organ mechanisms that can be therapeutically harnessed

Modeling the Exposome in Murine Cardiovascular Disease | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.jacbt…

Huge congratulations to Andreas Graur from the @UniHeidelberg for being awarded the prestigious Otto-Hess-Promotionsstipendium to support his one year research stay in the Poller lab @MGHHeartHealth @mghcvrc @harvardmed @DGK_org

Great pleasure and honor to deliver the keynote lecture at the 2026 Heidelberg/Mannheim DZHK Annual Retreat in beautiful Heidelberg! Thanks for hosting me @ Florian Leuschner, Gergana Dobreva, and Norbert Frey @dzhk_germany @harvardmed @MGHHeartHealth @mghcvrc

Congratulations!!! to @IgorPalacios3 , Interventional Cardiology legend @MGHHeartHealth and mentor to so many, on his Career Achievement Award from @crfheart at #NYValves2026. A wonderful heartfelt tribute delivered by Ignacio Inglessis.

I'm very excited to share that I will be joining @Amgen, overseeing cardiometabolic research and human genetics, starting Aug 3! I am excited to shape target identification, biology, and drug discovery as the therapeutic area head for cardiovascular disease, obesity, and general medicine. And I will lead the human genetics efforts, spanning Amgen deCODE genetics (a subsidiary of Amgen), that drive target discovery and biology across all therapeutic areas. I have been incredibly fortunate to interface with truly remarkable individuals and culture across @MassGenBrigham, @broadinstitute, and @harvardmed, where I could not have asked for a more meaningful and enjoyable academic career. Being able to build on my prior work, discover and clarify therapeutic hypotheses, and now carry them through to medicines that reach millions is an opportunity I'm grateful for. I'm very excited for what comes next.

Analyzing protein-coding variants across 1.2M individuals, our study by @skoyamamd identifies new targets for lipid and CAD therapeutics & informs genetic testing for Mendelian dyslipidemias nature.com/articles/s41588-0… @NatureGenet

#MGBInterventionalCardiology stars @BrianBergmark (VESALIUS-CV substudy) and @SuzanneJBaron (ShortCUT substudy) presenting in Hotline Sessions at EuroPCR today!

Grateful to share that I’ve been promoted to Professor of Medicine @harvardmed @Harvard. I am deeply thankful for my family, mentors, collaborators, and trainees who have carried me here.

Congratulations to Yven Israng from the Technical University of Munich for being awarded the prestigious Boehringer Ingelheim Fonds fellowship to support his one year research stay in the Poller lab at the MGB Heart and Vascular Institute. We are very happy to have you! @mghcvrc

📣 We’re hiring! The Lau Women’s Heart Lab at @MassGenBrigham is looking for a MD research fellow (patient-oriented 🫀research, epi) to join our team! Apply here tinyurl.com/3eb8byes or reach out to elau6@mgb.org to learn more.

We are thrilled to welcome Yven Israng, medical student @TU_Muenchen, and Andreas Graur, medical student @UniHeidelberg as new members of our lab! This is going to be an exciting year @mghcvrc @MGHHeartHealth @harvardmed

Beyond glucose and weight loss: GLP-1 RAs reduce systemic inflammation, atherosclerosis inflammation and progression, and MACE —independent of diabetes or obesity Key findings: * Using serial intravascular NIRF-OCT inflammation and IVUS imaging, liraglutide reduced plaque inflammation and plaque progression in rabbits without obesity or diabetes; * In the MGB Biobank, GLP-1 RA use reduced blood inflammation and MACE, regardless of A1c or BMI status; * In human macrophages, three GLP-1RAs suppressed inflammatory cathepsin protease activity; --> Intravascular NIRF-OCT offers the potential for inflammation imaging and anti-inflammatory drug assessment in human CAD --> Time to investigate GLP-1RAs in all patients with CAD? Collaborative, extended effort by @MohamadBKassab1 H.Khraishah A.Thrapp @ShadyAbohashem @ATawakolMD P.Libby @GTearney1 et al.  Our sincere thanks to the editors and reviewers @ehj_ed academic.oup.com/eurheartj/a…

Congratulations to @krosenfieldMD and colleagues on leading the HI-PIETHO trial presented and published today! An important study informing us on optimal treatment of of patients with intermediate risk PE. #MGBInterventionalCardiology Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism | New England Journal of Medicine nejm.org/doi/full/10.1056/NE…

If you are at the ACC meeting in New Orleans, please consider discussing your work with me. I will hold JACC: BTS editor-in-chief office hours on Sunday, March 29 from 3-5pm at the convention center. You can sign up here: forms.office.com/r/AtkbCWmTW…