🚨 NETHERLANDS COURT OVERRULES BILL GATES DISMISSAL BID 🚨 The Lawsuit: 7 Dutch citizens are suing Bill Gates, Pfizer's CEO, and local officials over COVID-19 vaccine safety claims. The Jurisdiction: A judge rejected Gates' attempt to throw out the case, ruling that Dutch courts have the international authority to force a defense. The Reality: This is a private civil dispute for financial damages, not a criminal indictment or arrest. No final verdict on liability has been reached. πŸ‘‰ Check out the complete global power map on Page 2 linking Bill Gates, Pfizer's CEO, and the head of NATO directly to this lawsuit: img1.wsimg.com/blobby/go/ee2…
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Replying to @cath2060
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πŸš— YOUR CAR COULD BE HACKED! 😱 Scientists just found 400+ software flaws in vehicles that let hackers kill your BRAKES or STEAL YOUR DATA. Is your ride safe? πŸ›‘πŸ‘‡ Core Discovery: Researchers uncovered 413 software vulnerabilities in cars by analyzing a government database. Major Risks: Flaws let hackers steal personal data or take control of your steering and brakes. Solution: Drivers should install software updates immediately. AI hacking introduces smarter threats, allowing criminals to automate malware creation and bypass vehicle encryption at scale. Notable Vehicles: The cars most frequently highlighted in automotive security research and real-world testing include: Jeep Cherokee Tesla Model 3 / Model S BMW 3 Series Lexus NX / Toyota Models Ford F-150 CITATIONS: University of Gothenburg Study: Published in the Software Quality Journal. Jeep Recall: Published via the official National Highway Traffic Safety Administration (NHTSA) Recall Database. Global Regulatory Mandates: Documented in the United Nations Economic Commission for Europe (UNECE) Regulation No. 155 (UN R155) #CarHack #CyberSecurity #TechNews
Made with AI
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πŸ€– AI bots are officially infiltrating bank accounts. πŸ“±β˜ οΈ This isn't a future warning, it's happening now. U.S. banks are struggling to contain rogue AI agents after security violations across major institutions. The line between helpful assistant and systemic threat is officially gone.
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Then don't bomb Iran you genocidal buffoon.
Marco Rubio on Iran: The Iranian regime is basically arguing that, "Unless we get what we want, we will destroy the energy infrastructure of the entire region." Just think about that. That's not normal behavior.
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IN THE HANDS OF BAD ACTORS NOT EVEN THE HALF OF IT WHAT HAPPENS IF THEY GET "THE CODES?" POSSIBLE!
BREAKING: Binance responds to ongoing situation regarding a suspected potential $2.8 billion hack. Full Statement Below:
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AI PLAYED A WAR GAME: Shocking Danger of Machine Escalation πŸ€– Total escalation: AI resorted to nuclear strikes rather than diplomacy. πŸ€– Never backing down: AI recorded a zero percent surrender rate. πŸ€– Ignored peace: Bypassed concession or tactical withdrawal.
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Replying to @dejanirasilveir
πŸ‡΅πŸ‡± POLAND'S PERSECUTION ENDED 1989, 37 YEARS AGO // BERLIN WALL REMAINS FRESH: Soviet Union and Polish communist punished dissent, religious freedom '45 to '89, 44 years. Arrests, censorship, economic hardship. 1,000s prisoned, killed. THAT'S WHY POLAND GETS IT ‼️ nitter.siddz.com/dejanirasilveir/status…
🚨IMPRESIONANTE POLONIA πŸ‡΅πŸ‡± ASÍ SE DEFIENDE SU PAÍS: Demostrando UniΓ³n y entonando su himno, Fuerza y DeterminaciΓ³n y PATRIOTISMO. Los polacos lograron detener el Golpe de Estado, convirtiΓ©ndolo en un Golpe Fallido πŸ‘πŸ‘πŸ‘ Polonia le ha dado UN GRAN EJEMPLO al mundo de como se defiende su SOBERANÍA y LIBERTADπŸ”₯
Community note
Misleading. The video has nothing to do with current events surrounding the Polish Constitutional Court. The footage was actually posted on YouTube on September 2026. piped.video/shorts/77hUXl1…
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Replying to @DrcharlieWardQ
NIGHTMARE. 😱 Absolutely terrifying because it hits so close to home. My family lived through a similar nightmare when my Native American relative was held hostage by a hospital in Santa Cruz, CA. It got so desperate and frightening that I had to call an ambulance service to literally hijack him out of there in the middle of the night just to save his life. We were completely trapped until Senator Dianne Feinstein and Sacramento miraculously stepped in at the 12th hour to rescue us. What is happening in these hospitals is a horror story, and more people need to speak out! nitter.siddz.com/DrcharlieWardQ/status/…
BREAKING 🚨: The hospital found out Gail Seiler was unvaccinated for COVID. Then they tried to MURDER her. They STARVED her for 12 days, denied her water for 7 days, and told her husband she was going to die. When her husband came to take her home, the hospital made her a PRISONER. They called the police, and a 6-hour standoff followed. When the hospital finally let them go, it wasn’t through the main entrance. It was through the freight elevator used to carry bodies to the morgue. On the way out, a nurse told her husband, Brad, β€œMark my words, she’ll be dead tonight, or before you even get home.” Gail survived. Not because of a miracle, but because a caring physician stepped in and guided her home treatment: nebulized budesonide and ivermectin. BRAD SEILER: β€œOver the next 30 days, she was weaned completely off of oxygen. Within 60 days, she had recovered sufficiently to return to work. Today, Gail is alive, healthy, active, and enjoying life with our grandchildren and children.” Gail’s story is horrendous, but it’s not uncommon. Hospitals were rewarded with perverse bonuses during COVID, and the more interventions they ran, the more they made. As Attorney @RenzTom previously testified: β€œWe have incentivized the MURDER of patients rather than incentivize TREATMENT.” β€œWhen you go to the hospital, you get tested. They get paid more. When you get admitted for COVID, they get paid more. When they put you on remdesivir, they get paid more. When you get ventilated, they get paid more. When you die, they get paid more. This is perverse.”
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The song being played is titled "Khodahafez" (Goodbye) by the Iranian pop folk artist Erfan Tahmasbi. Poetic Metaphors Explained: "The moon and the mirror left" In Persian poetry, the moon symbolizes ultimate beauty and light, while the mirror symbolizes clarity, self-reflection, and purity of heart. When the speaker says they both left, it means all the beauty, light, and honesty vanished from their life when the lover walked away. "The lump of sorrow in the chest" (Boghz): The word Boghz refers to that heavy, choking feeling you get in your throat or chest right before you cry. It represents unexpressed grief and pain trapped inside. "Alley of sorrows" An alley or neighborhood of sorrows is a metaphorical place of wandering. It implies that the speaker is lost in a continuous cycle of sadness and has nowhere else to go.
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Replying to @NicHulscher
"Spike protein and mRNA are found in EXOSOMES years after vaccination." 🫠 Now, into years? Goes back to the very beginning: 2019 That's it. GAME OVER.
We just found COVID mRNA shots have potential HUMAN-TO-HUMAN TRANSFER capabilities. Spike protein and mRNA are found in EXOSOMES years after vaccination. EXOSOMES are found in breast milk, saliva, breath, & sweat. EXOSOMES readily deliver biological cargo to distant cells.
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@audela_emma @verummultum @athiskemonn @Ryansikorski10 @DawnC1235 @PhoenixRose2Day @super1990 @Earthdriver @milehijules @F_K_Factor @keith_steinle @connerben @mcne73001 PROOF THEY'RE PREPARING THE BEAST SYSTEM !! Part 4 NWO NEURAL WAVE OPERATOR ASSEMBLY (ASM) & THE INTEGRATION OF SYNTHETIC BIOLOGY According to the New World Order (NWO) Theories it is suggested that the "Mark Of The Beast" (Revelation 13) could be a TECHNOLOGICAL IMPLANT on/in the forehead (controlling the frontal lobe/mind) or right hand, with some theorists LINKING THIS TO ADVANCED AI AND/OR NEURAL INTERFACES. NWO-ASM (Neural Wave Operator Assembly) Is not just a piece of infrastructure β€” IT IS A RESEARCH PROGRAM. The above statement is being LITERAL !!!! The whitepaper formalises THE PROCESS-MATRIX MODEL, the causal-coherence scheduling primitive, FREE-ENERGY ROUTING ACROSS 8 SUBSTRATE CLASSES, & THE VERIFICATION STACK (CRYSTALS-Dilithium Signatures Plus Groth16 zk Proofs) MAKES EVERY INFERENCE ON-CHAIN AUDITABLE. CRYSTALS-Dilithium: A Lattice-Based Digital Signature Scheme csrc.nist.gov/pubs/conferenc… Now standardized by NIST as ML-DSA (Module-Lattice-Based Digital Signature Algorithm), is a post-quantum CRYPTOGRAPHIC SIGNATURE SCHEME selected as the PRIMARY STANDARD FOR DIGITAL SIGNATURES in 2024 (FIPS 204). It is designed to secure data against threats from quantum computers, replacing traditional schemes like RSA & ECC. Groth16 zk Proofs Groth16 is a highly efficient zk-SNARK (Zero-Knowledge Succinct Non-Interactive Argument of Knowledge) protocol, widely adopted for its minimal proof size & rapid verification speeds. chainscorelabs.com/glossary/… It documents what is live today on Base 8453 and traces the open theoretical paths β€” from thermodynamic semantics of computation to long-horizon photonic, neuromorphic, DNA & crystalline substrates. WHITEPAPER us.aws.cdn.hf.co/xet-bridge-… OS for the Biological Foundry A compiler stack for SYNTHETIC BIOLOGY. cpater-nwo-genetic.static.hf… High-Level Biological Intent: - "PRODUCE PROTEIN X" - "Store this Archive" - Encode this Logic Gate inside this cell" - "prepare an entanglement vault" - "compose a CISS spin-gate" THE PRODUCTION OF PROTEIN X To Produce Protein X & Encode Logic Gates Inside a Cell, researchers use De Novo Design to create modular proteins that function as molecular logic gates (such as AND, OR, or NOR gates). REMEMBER SPARK 2? The Logic Gate operates by allosteric wiring or Protein-Protein INTERACTIONS (PPI), where specific input signals (e.g., CHEMICAL LIGANDS OR LIGHT) trigger conformational changes or assembly of protein subunits. THIS PROCESS ALLOWS THE CELL TO COMPUTE BIOLOGICAL RESPONSES, such as activating or suppressing a target gene (e.g., TIM3 to address T-cell exhaustion). genengnews.com/news/artifici… Why Protein-Level Gates Matter Traditional synthetic biology circuits operate at the DNA/RNA level (promoters, repressors, miRNAs), with response times of hours. Protein-level gates operate in seconds to minutes, are post-transcriptional (no need to reprogram the genome), and can be made fully orthogonal to native cellular machinery. This makes them ideal for: - Cell therapy (safer, more durable CAR-T and other engineered cells) - Biosensing (detecting disease markers in real time) - PROGRAMMABLE BIOMATERIALS (protein circuits Embedded In Hydrogels that respond to local biochemical cues) nature.com/articles/s41587-0… It compiles through NWO-ASM to a polymorphic Process-Matrix IR, dispatches to any qualified write substrate β€” enzymatic TdT, photolithographic chip, electrochemical semiconductor, microfluidic droplet, photonic synthesis, phosphoramidite, spin-injection, or wetware target β€” and is validated, fold-predicted, coherence-validated & runtime-error-corrected by NWO NEURO cpater-nwo-asm.static.hf.spa… The optional Chiral-Quantum Engine adds a typed σχ channel to the IR for chirality-aware compilation.
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Western civilization in action:
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AN AWARD-WINNING IRANIAN SHORT FILM THAT CHOKED ME UP ❀️ An elderly man notices a couple arguing in traffic, while their little daughter silently watches everything from the back seat. Seeing the little girl caught in the middle of their argument, he and his wife decide to do something to remind the family of the love they seem to have forgotten. Through a simple gesture involving flowers, they send them a heartfelt message. But the ending reveals something truly heartbreaking... The elderly man was never actually accompanied by his wife. He visits her grave every Thursday. The empty seat beside him holds nothing but memories of the woman he loved. The flowers he had originally brought for her were given to the arguing family instead, hoping to remind them of the love they still have. And the little girl’s response with a flower of her own makes the moment even more emotional. A man who can no longer share his love with the person he lost, yet still finds a way to bring a little love back into someone else’s life. 🫰
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Replying to @Fa21519230
BILL G&TES IS A M&SS MUR&ER and I'd venture to say he's sponsored by Global AI Governance. He is! What am I saying.
🚨🚨 Doctor ADVIERTE: "No existía el autismo en Vietnam en 1975"... "Hasta que Bill Gates introdujo el programa de vacunación"... "Vietnam tiene ahora un 300% de aumento en autismo"...
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These Luciferian technocratic bastards are gonna try to induce FEAR into the minds of the individuals who are pushing back against this technosphere by creating a false memory that's FEAR-based. Controlling the emotions of a person plays a huge role in our manufactured reality because this allows AI behavioral modification recommendations after thousands of simulations have been ran using predictive probabilistic computer models. In cognitive science, the human brain is viewed as a BAYESIAN PREDICTION MACHINE. The brain holds a "prior" (what it believes happened in the past) and uses sensory data to update its "posterior" (its current reality). AI targets the prior to modify your behavior!! Have you seen the public data bank that contains the biological magnetic resonance of humans call BMRB? The Biological Magnetic Resonance Bank (BMRB) bmrb.io is FAIR-based (FEAR-based). It proudly promotes it on its homepage. FAIR Principles go-fair.org/fair-principles/ The GO FAIR Foundation gofair.foundation/ The Decaprio movie Inception was predictive programming for the masses by the military-entertainment complex (MEC). researchgate.net/profile/Tan… Its the false memory (inception) of FEAR for the implementation of the FAIR (FEAR) principles with our biological metadata because FEAR is findable, accessible, interoperable, and reusable. All roads lead to the capturing of our biomagnetic resonance when we are in a state of FEAR! πŸ“„ Inception of a false memory by optogenetic manipulation of a hippocampal memory engram We first identified a population of cells in the dentate gyrus (DG) of the hippocampus that bear the engrams for a specific context; these cells were naturally activated during the encoding phase of fear conditioning and their artificial reactivation using optogenetics in an unrelated context was sufficient for inducing the fear memory specific to the conditioned context. In a further study, DG or CA1 neurons activated by exposure to a particular context were labelled with channelrhodopsin-2 (ChR2). These neurons were later optically reactivated during fear conditioning in a different context. The DG experimental group showed increased freezing in the original context in which a foot shock was never delivered. The recall of this false memory was context specific, activated similar downstream regions engaged during natural fear-memory recall, and was also CAPABLE OF DRIVING AN ACTIVE FEAR RESPONSE. Together, our data demonstrate that by substituting a natural conditioned stimulus with optogenetically reactivated DG cells that bear contextual memory engrams, it is possible to incept an internally and behaviourally represented false fear memory. pmc.ncbi.nlm.nih.gov/article…
A 🧡: Turning Humans into Applications (Apps) BioThings Application Programming Interface (API) Building a Findable, Accessible, Interoperable, Reusable (FAIR) API Ecosystem for Biomedical Knowledge. Findable, Accessible, Interoperable, Reusable (FAIR) (fairdatapoint.org/) is pronounced FEAR. Like the emotion. Semantics. πŸ“ biothings.io/ Just like when they bring the πŸ”₯ w/ Health Level 7 (HL7) Fast Healthcare Interoperable Resources (FHIR). HL7 FHIR fhir.org/ HL7 Foundry foundry.hl7.org/ Health Level 7 (HL7) Fast Healthcare Interoperable Resources (FHIR) is pronounced FIRE!!!!! πŸ”₯ πŸ”₯πŸ”₯ The FHIR πŸ”₯ adheres to the FAIR (FEAR PRINCIPLES) Principles!! They are bringing the FEAR (bio/physiological signals) thru enrolling people into clinical trials using their medical electronic health records (EHRs) & by GENERATING synthetic EHRs which then are displayed to the world as pandemics. (PLANdemics) clinicaltrials.gov/data-api/… cdisc.org/kb/articles/use-fh… ⚠️ Why the FUCK does synthetic (GENERATED!!) Electronic Health Records (EHRs) have an Application Programming Interface (API) to an International Standardization dealing w/ the exchange of Medical Electronic Health Records i.e. Health Level 7 (HL7) Fast Healthcare Interoperable Resources (FHIR)? ⚠️ They are raining hellfireπŸ”₯ πŸ”₯πŸ”₯upon the masses w/ the FEAR Principles!! cloud.google.com/healthcare-… synthea.mitre.org/fhir-api mitre.github.io/fhir-for-res… genrocket.com/newsletter/syn… healthit.gov/data/data-brief… govciomedia.com/hl7s-fhir-fo… sciencedirect.com/science/ar… arxiv.org/html/2506.13800v1 BioThings Application Programming Interface (API) Framework Making high-performance Application Programming Interface (API) for biological annotation data. github.com/biothings/biothin… BioThings Application Programming Interface (API) Specifications BioThings Application Programming Interfaces (APIs) are APIs designed 4 BIOLOGICAL ENTITIES!! Here are the guidelines to follow when building a new BioThings API. Why do you think they use that verbiage β€œENTITIES” ? biothings.io/biothings-specs BioThings Software Development Kit (SDK) BioThings SDK: A toolkit for building high-performance data APIs in biomedical research A generalizable & reusable toolkit 4 integrating data from multiple disparate data sources & creating high-performance APIs. This toolkit allows users to easily create their own BioThings APIs 4 any data type of interest to them, as well as keep APIs up-to-date w/ their underlying data sources. pmc.ncbi.nlm.nih.gov/article… BioThings SDK is built in Python & released via PyPI pypi.org/project/biothings/ BioThings SDK docs docs.biothings.io/en/latest/ MyGene.info Gene Annotation as a Service. mygene.info/ MyGene.info A BioThings API for gene annotations MyGene.info provides simple-to-use REST web services to query/retrieve gene annotation data. github.com/SuLab/mygene.info MyGene.info docs A typical use case is to use it to power a web application which requires querying genes & obtaining common gene annotations. 4 example, MyGene.info services are used to power BioGPS. docs.mygene.info/en/latest/i… MyGeneset.info docs MyGeneset.info provides simple-to-use REST web services to query, retrieve, & store annotation data for collections of genes. Access curated genesets from public databases, including: GO, KEGG, MSigDB, Disease Ontology/OMIM, Wikipathways, & Reactome. Filter genesets to an organism of interest. Retrieve gene collections w/ an identifier of choice. docs.mygeneset.info/en/lates… Scripps Institute | BioGPS biogps.org/mobile/ scripps.edu/ BioGPS The Gene Portal Hub A free extensible & customizable gene annotation portal, a complete resource for learning about gene & protein function. biogps.org/?full#goto=welcom… BioGPS Plugin Library Plugins are the backbone of BioGPS & can be combined into custom Layouts 4 viewing many at once. biogps.org/plugin/
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Replying to @Ryansikorski10
Amazing. All true. Blows the ever-lov'in mind. Per usual, impeccable research aligned with 5 links, no less ...all the bells & whistles align. Mr. Ryan, your credibility is off the chart. Can't you ever be wrong?
These Luciferian technocratic bastards are gonna try to induce FEAR into the minds of the individuals who are pushing back against this technosphere by creating a false memory that's FEAR-based. Controlling the emotions of a person plays a huge role in our manufactured reality because this allows AI behavioral modification recommendations after thousands of simulations have been ran using predictive probabilistic computer models. In cognitive science, the human brain is viewed as a BAYESIAN PREDICTION MACHINE. The brain holds a "prior" (what it believes happened in the past) and uses sensory data to update its "posterior" (its current reality). AI targets the prior to modify your behavior!! Have you seen the public data bank that contains the biological magnetic resonance of humans call BMRB? The Biological Magnetic Resonance Bank (BMRB) bmrb.io is FAIR-based (FEAR-based). It proudly promotes it on its homepage. FAIR Principles go-fair.org/fair-principles/ The GO FAIR Foundation gofair.foundation/ The Decaprio movie Inception was predictive programming for the masses by the military-entertainment complex (MEC). researchgate.net/profile/Tan… Its the false memory (inception) of FEAR for the implementation of the FAIR (FEAR) principles with our biological metadata because FEAR is findable, accessible, interoperable, and reusable. All roads lead to the capturing of our biomagnetic resonance when we are in a state of FEAR! πŸ“„ Inception of a false memory by optogenetic manipulation of a hippocampal memory engram We first identified a population of cells in the dentate gyrus (DG) of the hippocampus that bear the engrams for a specific context; these cells were naturally activated during the encoding phase of fear conditioning and their artificial reactivation using optogenetics in an unrelated context was sufficient for inducing the fear memory specific to the conditioned context. In a further study, DG or CA1 neurons activated by exposure to a particular context were labelled with channelrhodopsin-2 (ChR2). These neurons were later optically reactivated during fear conditioning in a different context. The DG experimental group showed increased freezing in the original context in which a foot shock was never delivered. The recall of this false memory was context specific, activated similar downstream regions engaged during natural fear-memory recall, and was also CAPABLE OF DRIVING AN ACTIVE FEAR RESPONSE. Together, our data demonstrate that by substituting a natural conditioned stimulus with optogenetically reactivated DG cells that bear contextual memory engrams, it is possible to incept an internally and behaviourally represented false fear memory. pmc.ncbi.nlm.nih.gov/article…
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Replying to @cath2060
Yes I can be wrong I am HUMAN. β€οΈπŸ‘Š I don't have Hachimoji DNA. Hachimoji DNA A synthetic DNA system that includes 8 nucleotide bases instead of the 4 found in natural DNA, allowing for the creation of new forms of life & new types of DNA-based technologies. Hachimoji DNA incorporates 4 additional building blocks (Z, P, S, B), allowing for more diverse possibilities in genetic information &, crucially, opening up new avenues in genetic research, synthetic biology, & nanotech. How proton transfer impacts hachimoji DNA pubs.rsc.org/ra/article/13/2… In a unique study, quantum biologists from Surrey investigated how protons move in Hachimoji DNA. Using a method called density functional theory, the team calculated the speed of proton transfer & how it's affected by temperature. They found that proton transfer happens more easily in Hachimoji DNA compared to regular DNA. Specifically, certain pairs of bases in Hachimoji DNA allow protons to move 30% faster than in regular DNA. This suggests that Hachimoji DNA might have a higher chance of mutations compared to normal DNA. surrey.ac.uk/news/more-mutat… Coupled w/ an engineered T7 RNA polymerase, this expanded DNA alphabet could be transcribed into RNA. Thus, new forms of DNA that add information density to genetic biopolymers can be generated that may be useful for future synthetic biological applications. Hachimoji DNA was then transcribed to give hachimoji RNA in the form of a functioning fluorescent hachimoji aptamer. science.org/doi/10.1126/scie… Synthetic Hachimoji nucleobases can be reliably sensed by analysing the strength & duration of characteristic electrical signals generated when their presence in a nanopore modulates the conductance of an adjacent carbon wire. pubs.rsc.org/nr/article/12/3… Synthetic Hachimoji DNA Sequencing w/ Graphene Nanodevice We have demonstrated quantum interference (QI) effects on the transverse conductance of Hachimoji (synthetic) nucleic acids placed between the oxygenterminated zigzag graphene nanoribbon (O-ZGNR) nanoelectrodes. We theorize that the QI effect could be well preserved in Ο€-Ο€ coupling between a nucleobase molecule & the carbon-based nanoelectrode. Our study indicates that QI effects such as anti-resonance or Fano-resonance that affect the variation of transverse conductance depending on the nucleobase conformation. Further, a variation of up to 2-5 orders of magnitude is observed in the conductance upon rotation for all the nucleobases. The current-voltage (I-V) characteristics results suggest a distinct variation in the electronic tunnelling current across the proposed nanogap device for all the five nucleobases w/ the applied bias voltage. The different rotation angles keep the distinct feature of the nucleobases in both transverse conductance & tunnelling current features. Both features could be utilized in an accurate synthetic DNA sequencing device. arxiv.org/abs/2203.08261 Sensing Hachimoji DNA Bases w/ Janus MoSH Monolayer Nanodevice The Janus MoSH monolayer shows promise as a metal contact material in high-performance nanodevices, forming a p-type Schottky contact that allows for efficient charge injection.[50]pubmed.ncbi.nlm.nih.gov/3487… Its electronic structure can be adjusted w/ external strain & electric fields, enhancing its suitability for optoelectronic applications & demonstrating versatility in heterostructures w/ other semiconductors.[54]pubs.aip.org/aip/jcp/article… Additionally, Janus materials, w/ their asymmetrical structure & dipole moment, are expected to improve DNA sensing by facilitating stronger dipole–dipole interactions w/ nucleobases. This capability enhances the sensitivity & selectivity of DNA sensors, making Janus MoSH a valuable candidate for advancing biosensing technologies in genetic research & diagnostics. Our goal is to determine key parameters such as binding energy, charge transfer, & the lowest energy configurations, which are critical for optimizing sensor performance. pmc.ncbi.nlm.nih.gov/article…
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Replying to @Ryansikorski10
Replying to @cath2060
Yes I can be wrong I am HUMAN. β€οΈπŸ‘Š I don't have Hachimoji DNA. Hachimoji DNA A synthetic DNA system that includes 8 nucleotide bases instead of the 4 found in natural DNA, allowing for the creation of new forms of life & new types of DNA-based technologies. Hachimoji DNA incorporates 4 additional building blocks (Z, P, S, B), allowing for more diverse possibilities in genetic information &, crucially, opening up new avenues in genetic research, synthetic biology, & nanotech. How proton transfer impacts hachimoji DNA pubs.rsc.org/ra/article/13/2… In a unique study, quantum biologists from Surrey investigated how protons move in Hachimoji DNA. Using a method called density functional theory, the team calculated the speed of proton transfer & how it's affected by temperature. They found that proton transfer happens more easily in Hachimoji DNA compared to regular DNA. Specifically, certain pairs of bases in Hachimoji DNA allow protons to move 30% faster than in regular DNA. This suggests that Hachimoji DNA might have a higher chance of mutations compared to normal DNA. surrey.ac.uk/news/more-mutat… Coupled w/ an engineered T7 RNA polymerase, this expanded DNA alphabet could be transcribed into RNA. Thus, new forms of DNA that add information density to genetic biopolymers can be generated that may be useful for future synthetic biological applications. Hachimoji DNA was then transcribed to give hachimoji RNA in the form of a functioning fluorescent hachimoji aptamer. science.org/doi/10.1126/scie… Synthetic Hachimoji nucleobases can be reliably sensed by analysing the strength & duration of characteristic electrical signals generated when their presence in a nanopore modulates the conductance of an adjacent carbon wire. pubs.rsc.org/nr/article/12/3… Synthetic Hachimoji DNA Sequencing w/ Graphene Nanodevice We have demonstrated quantum interference (QI) effects on the transverse conductance of Hachimoji (synthetic) nucleic acids placed between the oxygenterminated zigzag graphene nanoribbon (O-ZGNR) nanoelectrodes. We theorize that the QI effect could be well preserved in Ο€-Ο€ coupling between a nucleobase molecule & the carbon-based nanoelectrode. Our study indicates that QI effects such as anti-resonance or Fano-resonance that affect the variation of transverse conductance depending on the nucleobase conformation. Further, a variation of up to 2-5 orders of magnitude is observed in the conductance upon rotation for all the nucleobases. The current-voltage (I-V) characteristics results suggest a distinct variation in the electronic tunnelling current across the proposed nanogap device for all the five nucleobases w/ the applied bias voltage. The different rotation angles keep the distinct feature of the nucleobases in both transverse conductance & tunnelling current features. Both features could be utilized in an accurate synthetic DNA sequencing device. arxiv.org/abs/2203.08261 Sensing Hachimoji DNA Bases w/ Janus MoSH Monolayer Nanodevice The Janus MoSH monolayer shows promise as a metal contact material in high-performance nanodevices, forming a p-type Schottky contact that allows for efficient charge injection.[50]pubmed.ncbi.nlm.nih.gov/3487… Its electronic structure can be adjusted w/ external strain & electric fields, enhancing its suitability for optoelectronic applications & demonstrating versatility in heterostructures w/ other semiconductors.[54]pubs.aip.org/aip/jcp/article… Additionally, Janus materials, w/ their asymmetrical structure & dipole moment, are expected to improve DNA sensing by facilitating stronger dipole–dipole interactions w/ nucleobases. This capability enhances the sensitivity & selectivity of DNA sensors, making Janus MoSH a valuable candidate for advancing biosensing technologies in genetic research & diagnostics. Our goal is to determine key parameters such as binding energy, charge transfer, & the lowest energy configurations, which are critical for optimizing sensor performance. pmc.ncbi.nlm.nih.gov/article…
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