@biorxivpreprint Serial intravascular labeling resolves dynamic decidual NK residency and gestational remodeling toward T-bet-Low states biorxiv.org/content/10.64898… @StanicLabUW @VirumbralesMM @UWMadison

DREADDs work in humans, wow, this is amazing stuff: nejm.org/doi/10.1056/NEJMc26…

New cancer treatments could come from understanding how high blood sugar changes T cells in ways that make them better at fighting cancer and explain why type 1 diabetes has been associated with a decreased risk of cancer. Read more at AAI News & Views: ow.ly/pn0f5103QjY.

AAI member Kannan Thangamani, PhD, recently created a 15-part social media series titled Immunology in 60 Seconds, answering questions like “What is immune memory?” and “Is the skin part of the immune system?” Watch all the videos and share with a friend: ow.ly/OVzQ5103Ojh.

We shouldn't underestimate the power of vagus nerve modulation. Today the potential for Parkinson's disease. Noninvasively. Work in the experimental model @natBME nature.com/articles/s41551-0…

This Thursday, join Dr @Ya-Hsuan Ho, Neuro-immunologist, @TheCrick for our @Cambridgeimmuno seminar: 📢‘The Neural Brake on Anti-Tumour Immunity’ 📅4-5 PM, Thu 5 November 📍JCBC @CamBioCampus Explore upcoming seminars: buff.ly/MndQmd6 #CITIID #CIN #Immunology

Is the skull's bone marrow different from other bones? Yes, it is the most distinct 🧠 In Cell, using SHANEL and vDISCO clearing, we showed skull marrow mirrors brain inflammation on TSPO-PET in patients with neurological disorders 👇🏻 doi.org/10.1016/j.cell.2023.…

Scientists pay tribute to Marta Shahbazi Alonso and Tamara González Costa who died on their way to a developmental-biology meeting go.nature.com/4iTyNO1

I know how frustrating it is when an organoid model works in one lab but not another. I am excited about the NIH SOM Center, building validated protocols and open access for any researcher who needs them. nih.gov/som

In @ScienceMagazine: The @ElaineFuchsLab has identified specialized immune cells—which occupy the epithelial layers between the skin surface and its stem cells—and act as a system regulator to help skin respond to changing environmental conditions. 🔗: bit.ly/4BA0xP0

Thrilled to share that our team’s latest research has been published back-to-back in @NatImmunol! 🔬👇 These two companion papers reveal a fundamental shift in our understanding of macrophage origins across embryonic development and adult life. 🧵 (1/5)

🧠 Join us for our next Hidden Figures in Neuroscience event featuring Dr. Alexa Canady, the first Black woman neurosurgeon in the U.S.! 📅 November 3 | 12 PM ET Come learn about her groundbreaking career and contributions to medicine! 🔗 Register: tinyurl.com/BIN-Hidden-Figur…

Very excited to share our latest paper, out today in Cell, led by @ItzDipyaman! This project started out with a curiosity as to how and why irAEs happen. Even more peculiar is that WT mice never develop irAEs…and why was that? cell.com/cell/fulltext/S0092…

なんと！！！ ｢1gの無線顕微鏡で、動くマウスの脳を広く観察｣ Nature ･ ケーブルなしで神経活動を記録 ･ 8,500個超の神経細胞を同時に観察 ･ 複数個体の競争行動や、脳と脊髄の同時計測にも対応 ･ 自然な行動の中で、脳の広い領域が協調する仕組みを探る研究基盤に nature.com/articles/s41586-0…

Tesla in the US builds flying cars. Europe makes sure plastic bottle caps stay attached that you can hardly drink. While this is exaggerated to compare, unfortunately, I think the joke captures a serious problem. For more than 10 years, we have been talking about innovation, startups and making Europe competitive. Yet how many new global technology leaders have we created, especially in Germany? We have excellent scientists, engineers and ideas. So why are we falling behind? From my experience in science and biotech, one of the biggest problems is bureaucracy. We control almost every experiment, every purchase, every decision of a scientist. Endless approvals, regulations and administrative procedures. All of this costs time, money and, most importantly, takes away the freedom to be creative. How can we compete with the US or China when building the same thing takes us much longer and costs several times more? I think we need to start where innovation begins: basic research. Give scientists freedom, responsibility and resources. Judge them by what they achieve rather than how many procedures they follow. Of course, we need rules and accountability. But we have to stop treating every scientist as someone who cannot be trusted. We cannot create an innovative Europe by regulating every step of innovation.

🎉 Our paper is out today in @ScienceMagazine! How does the intestine maintain the right balance of cell types? We find that signalling rhythms matter! So proud of our three shared first authors, Sonja Weterings, @HiromuneEto & @jddeleede! 🔗 science.org/doi/10.1126/scie…

1/8 What remains undiscovered in the human kidney? 🔍 While building an integrated human kidney atlas for the Human Cell Atlas, we discovered new biology—presented in our new preprint, with highlights below. 🧵 biorxiv.org/content/10.64898…

Miss talking about microscopy :) Where does the Spike protein end up in the body? Using DISCO-seq, researchers like me can now explore this in 3D by mapping SARS-CoV-2 Spike S1 across the bodies of mice. Could this help us better understand #LongCOVID? biorxiv.org/content/10.64898…

Scientists have developed an open-source microlens-array miniature microscope that can image the brains of freely moving mice with both a large field of view and cellular-level resolution. @NBIC_PKU @Orangeroad2017 scim.ag/4hAWwAI

RT @Zhang_Suyang: 🚨🧬 We are seeking a PhD student and a postdoc to join our team at MRC-LMB and investigate co-transcriptional splicing usi…