Transplant Surgeon @UMMC | Associate Professor @UMmedschool | clinical & basic science researcher | #liver #kidney #pancreas #transplantation #stemcells #islets
Baltimore, MD
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Out now in @Nature: our paper on multimodal precision diagnostics in clinical xenotransplantation. Hyperacute rejection is largely solved. The next challenge is the immune injury hiding below the surface, and we propose a framework to see it early. doi.org/10.1038/s41586-026-1…
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Proud to see @AlexandreLoupy present our @Nature paper on multimodal precision diagnostics in clinical #xenotransplantation at the Big Xeno Session of #ASN Kidney Week in Denver. #KidneyWk nature.com/articles/s41586-0…
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Raphael Meier MD-PhD retweeted
Multimodal precision diagnostics in clinical xenotransplantation - Nature - goo.gl/alerts/LpFVpP #GoogleAlerts
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Raphael Meier MD-PhD retweeted
遺伝子改変したブタの臓器をヒトに移植した後のGVHRを正確に診断するためのマルチモーダルな取り組みについての総説。近年の異種移植の取り組みの経緯などにも言及があるようだ。Nature。
nature.com/articles/s41586-0…
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Grateful to have worked on this with such an outstanding team.
Multimodal precision diagnostics in clinical xenotransplantation - Nature - goo.gl/alerts/LpFVpP #GoogleAlerts
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So grateful to have worked on this with such an outstanding team.
遺伝子改変したブタの臓器をヒトに移植した後のGVHRを正確に診断するためのマルチモーダルな取り組みについての総説。近年の異種移植の取り組みの経緯などにも言及があるようだ。Nature。
nature.com/articles/s41586-0…
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Raphael Meier MD-PhD retweeted
New in @Nature: UMSOM researchers outline a roadmap for detecting immune rejection in pig-to-human organ transplants at the earliest, potentially reversible stage.
📰Read more: bit.ly/umsom-pig-transplant
#Xenotransplantation
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Out now in @Nature: our paper on multimodal precision diagnostics in clinical xenotransplantation. Hyperacute rejection is largely solved. The next challenge is the immune injury hiding below the surface, and we propose a framework to see it early. doi.org/10.1038/s41586-026-1…
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Raphael Meier MD-PhD retweeted
Congrats on the Nature paper. Shifting the focus from hyperacute rejection to the quieter immune injury underneath feels like the right next step for xeno. Which of your modalities tended to flag that hidden injury first, and how far ahead of clinical signs?
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Raphael Meier MD-PhD retweeted
Looking forward to having more data to start running some AI models hehe…
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Raphael Meier MD-PhD retweeted
Incredible work! Moving beyond hyperacute rejection to tackle hidden immune injury early will transform clinical decision-making in organ transplantation. Exceptional research! 👏
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Raphael Meier MD-PhD retweeted
ブタ異種移植で超急性拒絶が抑制可能になった一方、従来診断では捉えにくい免疫性移植片障害が課題となっていることを踏まえ、早期検出、個別化免疫抑制、将来の遺伝子編集戦略につなげるマルチモーダル精密診断の枠組みを提案した総説がNature誌に発表されました。
nature.com/articles/s41586-0…
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Raphael Meier MD-PhD retweeted
Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-11096-0Now that hyperacute rejection of pig xenografts can be reliably prevented, subtler immune-mediated graft injuries have emerged that conventional diagnostics often miss; a multimodal p
nature.com/articles/s41586-0…
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Raphael Meier MD-PhD retweeted
Here is our latest Xenotransplantation Literature Update for January –June 2026. This update highlights key publications and insights in the field during this time frame.
I am deeply grateful to @meier_raphael for his guidance and mentorship
onlinelibrary.wiley.com/doi/…
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Raphael Meier MD-PhD retweeted
Very glad to see this now in print: "Global Consultation for Clinical Xenotransplantation: International Xenotransplantation Association Consensus and Communiqué Update" onlinelibrary.wiley.com/doi/…
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