as this account has grown i’ve found myself filtering what i post more & sharing less of the personal content i used to, so i’ve made @softwavedd for a smaller circle where i'll share more personal posts + general non-ai yap. this second account is for people i talk to regularly and trust, but rather than messaging everyone individually i’m putting it here. if you think that sounds like you, feel free to request :] i’ll also be less active here over the coming months as my priorities shift elsewhere - more on that when the time is right! as always, thank you for your support!! it means a lot if i might not recognise you from your twitter profile, just dm me here with a reminder of how we know each other.

Cancer patients with the same diagnosis often have very different tumor biology. Molecular testing can reveal underlying differences, but that's slow and expensive. Introducing Holon-S1, our platform to predict genes and biomarkers from routine pathology slides. • beats two other models at predicting spatial gene activity in a controlled comparison • has identified potentially novel biomarkers in breast cancer and colon cancer • evaluated across 16 organ types and more than 15 scanners, using slides from both formalin-fixed, paraffin-embedded and fresh-frozen tissue. We believe Holon-S1 has the potential to help researchers find new biomarkers in slides they already have, discover treatment targets, and bring more personalized cancer care within reach!

am i the only one that thinks it’s quite funny that we’ve seen very little from the big chinese labs in a while 🤔 (i do hope that changes, the big 2-3 american labs need better competition..)

4o was truly a special model

how are we falling for this.. come on now, tibo is not going to have set up a “opensi.lol” with a stripe donation form 🤦‍♂️ even if the person behind this has since removed that. clever from the person who created it because some accounts will just amplify anything!

Kinda bored of Anthropic keeping the mandate of heaven for so long And no, a Terra model ain’t gonna cut it 💔

Stock up on popcorn this week. You’ll need it

fable 5.5 needs to be really, really good to justify using it over opus given how much usage it burns, and i don't know if it's going to be that much better than it tbh (they could also go the price cut + a bit better route!)

are we fr

We discovered a sophisticated recording device that was hidden inside one of our offices. We used our models to understand the device and where it had come from, identifying that a specific employee had planted it a few days earlier. We referred the matter to the FBI, and we’re grateful to the agents and prosecutors who moved quickly to make an arrest. The FBI’s investigation is ongoing and we will continue to support their work. At this time, we have no indications of this individual inappropriately accessing or exfiltrating model weights, source code, or customer data. The employee was terminated. We take protecting our technology, data, and people seriously, and as a matter of national importance. Our security program is designed to protect against a wide range of threat actors, from insider risks to cybercriminals to nation states, and this case is an example of how AI can help address these sophisticated security threats.

Gemini 4 Argon is the new state-of-the-art on SimpleQA Verified, a world knowledge benchmark that in my experience has reflected my personal vibes-based judgement Super impressive that 3.1 Pro held up for so long though! It took 7 months for a model to dethrone it (GPT-6 Astra)

I dropped $5 to test Argon on my niche US politics knowledge question that has eluded every model except the Fable currently being stealth tested. If there's one thing Argon should be getting right it's this! But it got it wrong and hallucinated 🥀

And yes, for those asking, I'm told Fable 5.5 is slated for this week. I wouldn't be surprised if it dropped today but later in the week is also a possibility, barring any late hold-ups Better yet (and at long last!), OpenAI intend to ship 6.1 Astra during their 28 Days of Shipping this month Enjoy your brief time in the limelight little Argon 🫶

Gemini 4 Argon is now globally available. Built to solve your hardest problems from start to finish, the model brings frontier capabilities across coding, enterprise workflows, and cyber defense.

As I said! Happy Gemini 4 Argon day to those who celebrate 🍿 I have low expectations, but all I want is for the model to be as good for world knowledge tasks as Gemini 3/3.1 Pro were