Our lab @Buckinstitute studies molecular mechanisms of aging with focus on the cellular recycling process called autophagy
San Diego, CA
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Malene Hansen Lab retweeted
Thanks to all for a great 2025 NIA Summer Training Course this week at Buck! With a brilliant group of trainers, inspiring faculty talks, panel discussions, paint night, we all had a blast! Each one of you trainees are poised to shape the future of aging research!
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Excited to see our latest work on autophagy published - great work by former and current Hansen lab members at @sbpdiscovery and @BuckInstitute, in collaboration with Jeff Kelly's lab at @scrippsresearch!
Study in @PNASNews highlights small molecule that boosts autophagy, our cells’ cleanup system. AA-20 reduces fat & protein buildup in conserved fashion, extending health/lifespan in worms, w/out blocking mTOR. Congrats to @thehansenlab and Kelly labs! pnas.org/doi/10.1073/pnas.24…
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Very proud to be part of WIA @WAutophagy, and all the everything it has accomplished so far! Too many needs to be acknowledged, but a very special thanks to Dr. Ana Maria Cuervo and the Cuervo lab @AMCuervoLab! Check out this nice piece to learn more:
nature.com/articles/s41556-0…
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BIG and well deserved congrats to Jennifer Ellisseef, who is "really taking the SASP to the next level!" (as beautifully said by Peter Adams @AdamsBioAging)
Congratulations to Dr. Jennifer Ellisseeff, from @JohnsHopkins, for winning the inaugural Glenn-Campisi Award for Excellence in the Research of Aging at Buck, sponsored by Glenn Foundation for Medical Research to honor the legacy of Judy Campisi.
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Thank you @AFARorg for all your support over the years, and for this nice piece!!
Not only has Malene Hansen, PhD, received four AFAR grants & our 2021 Irving Wright Award, but she’s also advancing #autophagy research & mentoring future geroscientists.
Learn more in AFAR’s 2023 Annual Report here: afar.org/2023-annual-report @thehansenlab @BuckInstitute
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There is still time to register for the Glenn Campisi Celebration of Life Symposium on August 12 @BuckInstitute - register here: buckinstitute.org/events/cel…
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Indeed, very proud and grateful to be the recipient of the 2024 Bennett Cohen Award - thank you @UMich!
Congrats to our own Malene Hansen, @thehansenlab, recent recipient of the 2024 Bennett J. Cohen Award @UMich for her contributions to research on aging. Buck professors Judy Campisi and Gordon Lithgow are past recipients along with a who’s who of leaders in the field. Well done!
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BIG congrats to Hiroshi Ebata @ronbuntamago from @thehansenlab for winning poster prize at this week's Bay Area Aging Meeting - great representation for @BuckInstitute! (credit for picture @TheWebbLab)
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Malene Hansen Lab retweeted
As we mourn loss of and celebrate life of Judy Campisi, enjoy listening to interview she did for our podcast. It’s great tutorial on #cellularsenescence and her comment on “failed experiments” is classic Judy. Details about memorial service are pending buckinstitute.org/podcasts/u…
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Highlight of the summer, and looking much forward to this - thanks for co-organizing @RPWLab and @TheDouglasLab and @phillips_lab!
Registration is OPEN for #MAPSS2024: The best C. elegans conference on Planet Earth. Check it out the list of the scientists who will be at this meeting!!! 👇👇👇
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Malene Hansen Lab retweeted
I'm deeply saddened to share that we have lost a remarkable friend, a wonderful mentor and esteemed colleague, Judith Campisi. Judith's impact on those around her was profound and lasting. Her legacy will continue to inspire us all. Rest in peace, Judy. You will be greatly missed
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Very excited to share our latest work on non-canonical autophagy and aging @NatureAging - thanks to all of the co-authors @Buck, @sbpdiscovery and @RutgersU! Big cudos especially to Assistant Professor Dr. Caroline Kumsta @Kumsta!
Online now! Yang et al. show that inhibition of early-acting autophagy genes in neurons extend C. elegans lifespan, improve proteostasis, and increase #exopher formation via the autonomous WD40 domain-related function of ATG-16.2. @kumsta @thehansenlab rdcu.be/dvaFk
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Thanks to all the co-authors of this cool study @BuckInstitute and @sbpdiscovery - especially Assistant Professor Caroline Kumsta @kumsta!
Congrats to @thehansenlab for study in @NatureAging that describes new roles for autophagy genes in cellular waste management and aging. Researchers show that #autophagy genes help extrude protein aggregates from neurons in #Celegans. buckinstitute.org/news/new-r…
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Congrats to all co-authors on this nice work by Manish Chamoli @manish_chamoli in Julie Andersen's @JKAndersenBuck lab at @BuckInstitute - thanks for including us @thehansenlab and @kumsta !
Excited to share our latest research: MIC, a benzocoumarin molecule that enhances #longevity in #celegans by triggering #mitophagy. Our findings also show MIC's effectiveness in mammalian cells, indicating potential broader application. Full text here: rdcu.be/dqZmE
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Great aging meeting in Dubrovnik - thank you @Fusion_Conf !
Look at this wonderful view....the backdrop isn’t too bad either! 😉 #Fusionaging23 #sunseaandscience @CochemeLab @Joris_Deelen @MartinD79 @FrydmanLab @ShukryHabib_Lab @thehansenlab @JonesLabUCSF @BKennedy_aging @DrMorganLevine @Awartiovaara @MattYousefzadeh @iDikic2
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Excited to be at 4th interventions in Aging conference @Fusion_Conf in Dubrovnik - chaired by Linda Partridge & Henri Jasper!
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Malene Hansen Lab retweeted
Live from the Lab! Here’s what Saam Doroodian, Research Associate in @thehansenlab is up to! He’s studying the cellular recycling process in C. elegans to uncover similar biological processes in aging humans in order to keep our cells and tissues healthy #autophagy
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Malene Hansen Lab retweeted
In their Review, Jose Nieto-Torres, Sviatlana Zaretski, Tianhui Liu, Peter Adams and Malene Hansen summarise the post-translational modifications of ATG8 family proteins that influence the autophagic process.
journals.biologists.com/jcs/…
ALT Examples of molecular events controlled by ATG8 PTMs, including abundance, subcellular localisation, vesicle targeting and protein-protein interactions.
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Excited and honored to be part of the George Martin Memorial Geroscience Symposium 2023 Sept 11-12. (Registration: docs.google.com/forms/d/e/1F…)
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