Principal investigator / Postdoc in neuro-oncology @MedUni_Wien. Former @hovestadt lab member @DanaFarber. Interested in molecular mechanisms in brain cancers.

Vienna, Austria
Thrilled to share that our paper is out in @NatureCancer! We used #scRNAseq, multiplexed spatial imaging, and eCLIP to study the cellular cooperation and transcriptional network in C19MC-driven #ETMR. @beck_lab, @FilbinMariella, @hovestadt & Kool labs. nature.com/articles/s43018-0… 1/
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We identify distinct cellular cooperation of malignant cell types. Targeting this cooperation network with #FGFR and #NOTCH inhibitors is highly effective in ETMR cells. Importantly, #erdafitinib therapy resulted in partial response in one heavily pre-treated ETMR patient. 6/
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Appreciation to @DanaFarber, @BostonChildrens, @broadinstitute, and everyone who contributed and collaborated on this project, especially @gojojohannes and the @MedUni_Wien neuro-oncology team. 7/
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💥 We are #hiring! 💥 We are looking for a highly motivated #PhD fellow 👨‍🎓👩‍🎓and a biomedical #scientist to join our team focusing on pediatric brain cancer research. Know anyone who might be interested? 🧠💻 meduniwien.ac.at/web/karrier… meduniwien.ac.at/web/karrier…
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Thrilled to present our exciting #ETMR project at the #sno2023 pediatrics session! 🤩
Terrific talk by ⁦@LisaGblr⁩ on our joint ⁦@hovestadt⁩ @filbin Kool lab ETMR story! 🎊🎉
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Thrilled and humbled to announce that I’ve been awarded the #APART-#MINT fellowship. Grateful to pursue my research on novel #medulloblastoma therapies. Thanks to the Austrian Academy of Sciences @oeaw for believing in me. 👩🏻‍💻👩🏻‍🔬✨ © ÖAW/Natascha Unkart
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Got amazing news from @oeaw! Our APART-MINT proposal on novel approaches for medulloblastoma therapy got accepted! 🥳🤩 So excited to finally start this project with @hovestadtlab @gojojohannes @FilbinMariella 🧠 🧬 🔬 🐁
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Is there a better way to celebrate the #internatinalWomensDay than by picking up a research grant certificate? 💃 👩🏻‍💻 🧬 🧠 🧫 #WomenInScience #collaboration #fightkidscancer
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Lisa Gabler-Pamer retweeted
Therapy for human #braintumours 🧠➜ Find out how a whole-genome scan for #Artemisinin cytotoxicity reveals the novel therapy option. #OpenAccess in @EmboMolMed! ➡️ bit.ly/3RFm1nn #MedUniVienna, @LisaGblr, @andreaspeyrl, @IMBA_Vienna, @UBC, @viennabiocenter
Happy to share our latest study on novel therapies against high-risk brain tumors led by JM Penninger @IMBA_Vienna. Fantastic use of our patient-derived tumor models @MedUni_Wien to prove preclinical activity of novel therapeutic approaches! 🔬👇
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What an inspiring day at the @GRO_Broad Retreat with the @hovestadtlab! 🧬 #collaborations #innovation #technology
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Doing some serious business today at the @DanaFarber Cancer Biology Holiday Party 🎉 🥸
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Very exciting and important work - I really enjoyed reading the preprint! 🧠 🧫
📢Preprint alert! Here's our latest story, led by @catarinacsmc Brain organoid morphogenesis can be driven by exogenous ECM (Matrigel), or self-sustained by endogenous ECM production. Late development is mostly independent of the initial ECM source tinyurl.com/5n6n9ss3 🧵1/7
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Huuuuge congrats to my friend and first author @IlonLiu, and the equally contributing co-first authors Li Jiang, and Erik Samuelsson from the awesome groups of @FilbinMariella and @MatsNilssonLab! 🥳 💃 🎉
1/How do age and anatomical location shape H3-K27M gliomas' intrinsic and extrinsic features❓Very excited to share this work together with Li Jiang, Erik Samuelsson, @MatsNilssonLab and @FilbinMariella , published today @NatureGenet❗️rdcu.be/c02lT
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Woke up with good news from the @FWF_at today: My ESPRIT grant application was approved, funding 3y of research on medulloblastoma cellular heterogeneity 🥳🥳🥳 Let’s pop the corks! 🍾 @hovestadtlab @gojojohannes @FilbinMariella @drpaulnorthcott
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Christmas time has begun in the @hovestadtlab 🎄🤶
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