Principal investigator / Postdoc in neuro-oncology @MedUni_Wien. Former @hovestadt lab member @DanaFarber. Interested in molecular mechanisms in brain cancers.
We identify distinct cellular cooperation of malignant cell types. Targeting this cooperation network with #FGFR and #NOTCH inhibitors is highly effective in ETMR cells. Importantly, #erdafitinib therapy resulted in partial response in one heavily pre-treated ETMR patient.
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Got amazing news from @oeaw! Our APART-MINT proposal on novel approaches for medulloblastoma therapy got accepted! 🥳🤩
So excited to finally start this project with @hovestadtlab@gojojohannes@FilbinMariella 🧠 🧬 🔬 🐁
Happy to share our latest study on novel therapies against high-risk brain tumors led by JM Penninger @IMBA_Vienna.
Fantastic use of our patient-derived tumor models @MedUni_Wien to prove preclinical activity of novel therapeutic approaches! 🔬👇
📢Preprint alert! Here's our latest story, led by @catarinacsmc
Brain organoid morphogenesis can be driven by exogenous ECM (Matrigel), or self-sustained by endogenous ECM production. Late development is mostly independent of the initial ECM source
tinyurl.com/5n6n9ss3
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Huuuuge congrats to my friend and first author @IlonLiu, and the equally contributing co-first authors Li Jiang, and Erik Samuelsson from the awesome groups of @FilbinMariella and @MatsNilssonLab! 🥳 💃 🎉
1/How do age and anatomical location shape H3-K27M gliomas' intrinsic and extrinsic features❓Very excited to share this work together with Li Jiang, Erik Samuelsson, @MatsNilssonLab and @FilbinMariella , published today @NatureGenet❗️rdcu.be/c02lT
Woke up with good news from the @FWF_at today: My ESPRIT grant application was approved, funding 3y of research on medulloblastoma cellular heterogeneity 🥳🥳🥳
Let’s pop the corks! 🍾
@hovestadtlab@gojojohannes@FilbinMariella @drpaulnorthcott