Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).

Interested in lipids and lipid droplets? This is the meeting to attend this summer! See you there! 🤩

Free webinar: Quantitative Cell Biology Keynote + lightning talks from early-career researchers June 22 | 12 PM ET ascb.org/ascb-meetings/mboc-…

Great news! Early registration for the FASEB #LipidSRC has been extended until June 14! It is not too late to submit an abstract and present at the premier North American #LipidDroplet meeting events.faseb.org/event/544fc…

Our review dissecting the nuanced roles of mitochondria during cancer progression was just published in @AnnualReviews of Cancer Biology. This was driven by grad student David Sokolov, who wrote it in an approachable and entertaining style. Check it out: annualreviews.org/content/jo…

Looking forward to this conference 😍

You do not want to miss the 2026 FASEB #LipidDroplet conference! Abstracts are due May 31. Travel awards are available for trainees 👇

New paper from the lab, lead by graduate student Liang Chen. Here, guided by genome-wide CRISPR screening, we demonstrated that either lipids have a big impact on the lysosomal function, especially under the storage disease conditions. link.springer.com/10.1038/s4…

Looking forward to this 😍

Thank you @focalplane_jcs for highlighting our latest study! #NCI #NIH #LiverZonation #Microscopy focalplane.biologists.com/20…

Thank you, @BPoD_s, for highlighting our research at the Intramural Program National Cancer Institute! #NCI #NIH #LiverZonation #lipid #mitochondria

Mesmerizing light sheet imaging of neutrophils swarming at a yeast target! The neutrophils were labeled with SPY650-DNA (yellow) and a calcium dye (blue). This movie is part of the recent manuscript by Evelyn Strickland that we highly recommend reading! biorxiv.org/content/10.64898…

Abstract submissions for Cell Bio 2026 are now open Share your latest research with the global cell biology community & connect with peers from around the world. Submit by June 9 for full consideration. Late-breaking abstracts are accepted through Aug 4. ascb.org/cellbio2026/abstrac…

Check out our highlight of the most recent example of subcellular mitochondrial specialization in @CurrentBiology. Be sure to also check out the beautiful work from David Sherwood's lab cell.com/current-biology/ful…

F Rosenberger, @PoratShliomLab, M Mann et al. (Max Planck Inst of Biochemistry, @theNCI) Using single-cell Proteomics, the authors develop a resource providing spatially resolved proteomic analysis of individual cells in human liver tissue. dlvr.it/TS9SSb

How does a cell learn? In our new perspective in @Nature we propose a model where the properties of the AP-1 family of transcription factors – stress-induced feedback, regulatory combinatorics & cellular memory – encode a mechanism for cellular learning. nature.com/articles/s41586-0…

Neuronal lipid droplet-derived lipids support neuron function by providing fatty acids and phospholipids to sustain mitochondrial and endoplasmic reticulum function and homeostasis. nature.com/articles/s42255-0…

3D single-cell maps of embryos reveal "universal" geometry of blood vessels and nerves. More here: biorxiv.org/content/10.64898…

I am very happy to share that our paper is now published in @Nature 😊 Cell-type-targeted mitochondrial transplantation rescues cell degeneration. nature.com/articles/s41586-0… @IOB_ch (1/6)

Today in @natBME we report an in vivo base editing strategy that corrects a common disease-causing mutation and rescues pathology in a mouse model of Zellweger spectrum disorder (ZSD) and restore peroxisomal function in patient derived cells. This work highlights the promise of precision genome editing for treating peroxisomal biogenesis disorders. 1/13

Beautiful work from the @SItzkovitz lab mapping the healthy human liver at the transcriptomics level 😍