PhD | Endothelial dysfunction in vascular disease @UHN • MD Student @UofTMedicine • 🐱☕🚴🏋️🇨🇦
Toronto, Ontario
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#EndothelialDysfunction is a critical driver of #atherosclerosis, but how can EC identity be preserved to limit plaque progression?
Thrilled to share my final PhD work in @NatureComms: bit.ly/4fxmpl7
@kat_howe @FishLab_UHN @PMunkCardiacCtr @UHN_Research @UofTVascular
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Steven Botts retweeted
👏Congratulations to Dr. Giuseppe Papia on being named president-elect of the Canadian Society for Vascular Surgery (CSVS); a tremendous honour reflecting the respect & confidence of the national vascular surgery community. His term as president will begin in Oct 2027.
ALT Dr. Giuseppe Papia named president-elect of the Canadian Society for Vascular Surgery (CSVS)
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Steven Botts retweeted
(1/2) Congratulations to Drs. Mamatha Bhat and @kat_howe, inaugural recipients of the SUMO–UHN Distinguished Physician Investigator Award. 🎉
🔗 Read more: uhnresearch.ca/news/10-02-20…
ALT Portraits of two smiling female researchers with institutional logos and text.
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Steven Botts retweeted
New research from @UHN’s @PMunkCardiacCtr shows that the protein ERG helps protect blood vessels from changes that drive atherosclerosis—the buildup of plaque in the arteries. Findings could point to future therapeutic strategies to protect arteries.
🔗: uhnresearch.ca/news/9-04-202…
ALT Illustration of a heart beside a cross-section of an artery narrowed by plaque buildup, with red blood cells flowing through the vessel, depicting cardiovascular disease.
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Steven Botts retweeted
Reposting - our new story - now available for all! Open access. nature.com/articles/s41467-0… Thank you @NatureComms for the incredible editorial work and review process. Hard work that led to a transformative paper! Congrats team @SRBotts @kat_howe @FishLab_UHN
#EndothelialDysfunction is a critical driver of #atherosclerosis, but how can EC identity be preserved to limit plaque progression?
Thrilled to share my final PhD work in @NatureComms: bit.ly/4fxmpl7
@kat_howe @FishLab_UHN @PMunkCardiacCtr @UHN_Research @UofTVascular
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#EndothelialDysfunction is a critical driver of #atherosclerosis, but how can EC identity be preserved to limit plaque progression?
Thrilled to share my final PhD work in @NatureComms: bit.ly/4fxmpl7
@kat_howe @FishLab_UHN @PMunkCardiacCtr @UHN_Research @UofTVascular
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Our heartfelt thanks to colleagues who helped make this work possible:
@CoreyScipione @Kristen_ESchulz @SnehaRajuMD @Kamalben_Prajap @chanelekpolenz @clintomics @MyronCybulsky @uoftmedicine @uoftmdphd @UofTSurgery
Figures adapted from our Nature Communications paper.
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ERG preserves endothelial identity to limit atherosclerosis:
Full paper out now in @NatureComms !!
doi.org/10.1038/s41467-026-7…
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Steven Botts retweeted
A new study in @NatureComms, led by @UHN collaborators including Drs. @kat_howe and Jason Fish investigate the role of the ETS transcription factor ERG, a key regulator of #endothelial identity, in atheroprogression. 🧫 go.nature.com/4pzZB7Z
They identify ERG as an enforcer of endothelial function that restricts 🚫 endothelial‑to‑mesenchymal transition to limit atherosclerosis.
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Steven Botts retweeted
This football match is like watching somebody tweak their UMAP hyperparameters for 90 minutes on twitch.
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Steven Botts retweeted
Congrats to @SRBotts, @kat_howe & @FishLab_UHN labs at @UHN for this work. The importance of #endothelial health/identity in #atherosclerosis cannot be understated! ERG dysregulation in #cardiovascular health in #rodents and translated to #human #aortic disease.
#EndothelialDysfunction is a critical driver of #atherosclerosis, but how can EC identity be preserved to limit plaque progression?
Thrilled to share my final PhD work in @NatureComms: bit.ly/4fxmpl7
@kat_howe @FishLab_UHN @PMunkCardiacCtr @UHN_Research @UofTVascular
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Steven Botts retweeted
Congrats!!👏🏼 Massive tour de force by an amazing team. See this incredible work 🙏
#EndothelialDysfunction is a critical driver of #atherosclerosis, but how can EC identity be preserved to limit plaque progression?
Thrilled to share my final PhD work in @NatureComms: bit.ly/4fxmpl7
@kat_howe @FishLab_UHN @PMunkCardiacCtr @UHN_Research @UofTVascular
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Steven Botts retweeted
The aorta doesn't get enough respect. Even though it's uncommon, in someone who presents with chest pain, especially severe, we were trained to rule out aortic dissection before anything else.
Most likely Senator Graham had a Type A dissection and longstanding hypertension. If obtained previously, an echocardiogram or other image may have revealed a widening or aneurysm of the thoracic aorta.
nature.com/articles/nrdp2016…
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Steven Botts retweeted
Getting a cholesterol screening is a lot less complicated than memorizing all of Scorpion’s finishers. Just call your doctor and ask for a simple blood test.
#MortalKombatMovie #MortalKombat
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