Synthetic Neurobiology Lab @BCMhouston & @RiceUniversity. Our mission is to develop new molecular tools to accelerate the pace of biomedical discovery
Houston, TX
Based in United States
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🚀 Exciting Opportunity Alert! 🚀 Join our dynamic team at St-Pierre Lab at BCM as a Postdoctoral Researcher! Work on cutting-edge projects and contribute to groundbreaking discoveries. Apply now and be part of our innovative research community! #Postdoc #Opportunity
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Putting the final touches on my upcoming talk for the @CNPviralvectors satellite meeting at the @CAN_ACN conference, all while enjoying the stunning views of beautiful @CityofVancouver, my beloved home country of Canada!
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@HelenXiaoyuLu couldn't come to Houston to accept her @RiceSSPB thesis award, so I brought it to her in Seattle!
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Congrats to @HelenXiaoyuLu, an outstanding recent lab alum who won a @RiceSSPB thesis award 🏆! Xiaoyu is now a Scientist at @AllenInstitute and so couldn't attend. I attempted to accept on her behalf, disguised with her face on cardboard🎭, but my cover was blown quickly!
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🥂Celebrating 5 incredible years with Shujuan Lai in our lab @bcm_neurosci. She's been pivotal in developing photostable fluorescent proteins and our SPOTlight single-cell screening platform. She gave an inspiring speech🎤emphasizing the power of grit in achieving dreams.
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Dr. Francois St-Pierre led an illuminating session on "Advanced Concepts in Voltage Imaging" at the Optogenetics and Wavefront Shaping program in Paris. Unlocking new insights into brain functioning! #Neuroscience #Optogenetics #ParisConference 🌟
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Saying goodbye to Xiaoyu Lu with a memorable lunch!🔬🤠Your success in the lab has been nothing short of amazing. Saying goodbye is tough, but we're excited for your next steps. Can't wait to see your future achievements! Best wishes, Xiaoyu! #FarewellXiaoyu
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🎉 Congratulations to Shujuan Lai on her well-deserved promotion to Research Associate in the St-Pierre lab! 🙌🔬 Your dedication and hard work have truly elevated our research efforts. Thank you for being an invaluable part of our team! 🌟 #ResearchExcellence #TeamWork 🎊👏
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Big thanks to Prof. Dieter Jaeger for inviting me to the Emory U. Bio seminar series last week, and to Malia Escobar for ensuring a seamless visit. Loved engaging with the brilliant grad students and faculty. Astonished by Emory's massive neuroscience network – over 120 labs!
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Excited to have celebrated Xiaoyu Lu's Commencement earlier this week! A brilliant alum of @RiceUniversity, Xiaoyu pioneered the creation of groundbreaking Genetically Encoded Voltage Indicators for rapid brain imaging. Can't wait to see her future breakthroughs!
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🌟Join the St-Pierre Lab!🌟 We are looking for a passionate and innovative Postdoctoral Researchers. Join us to develop genetically encoded voltage indicators and other protein tools to accelerate
neuroscience research! More info ➡️ visit out website 🌐stpierrelab.com
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The St-Pierre will host a career both this Monday at #SfN23. Booth 3 at 1pm! Check out lab based in Houston stpierrelab.com/research where we develop protein tools for neuroscience research !
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🌟 Spotlight Moment!🌟 Nathan, one of our talented undergraduate students, made headlines in the RICE News Letter! Check out this snapshot of him sharing his groundbreaking research with an attentive group! #BCM #RICE #UndergraduateResearch
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"Surprised to discover my office door adorned by my amazing lab members to congratulate me on achieving tenure! 🎉🙌Clear East-West fusion! Considering leaving it up as a source of motivation until I reach Full Professor status? 🤔#TenureDoor
Thrilled to share the news of my promotion to Associate Professor! Immense gratitude to @PaulPfaffinger, our Chair at @bcm_neurosci, the dedicated Promotion Committee, and the stellar administrative team in our department for their relentless support! 🎉#AssociateProfsArePowerful
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A picture I took of a pond in Houston Arboretum, where I hiked last weekend. It was a gorgeous day. Houston is big and flat, but there are beautiful spots to engage with nature.
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Proud to announce that our own Dr. Michelle Land from the St-Pierre lab has clinched the 1st place award for postdocs at the 2023 @WelchFoundation Conference for her poster on "Enhancing Genetically Encoded Voltage Indicators for 2P Voltage Imaging In Vivo" #PostdocAchievement".
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Observing the partial solar eclipse from Houston, Texas, using pinholes on a cardboard to project an image onto my floor. The photos demonstrate that smaller pinholes gives a sharper image, as expected. #EclipseSolar #Eclipse2023
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A belated reply to say I'm honored to be a recipient of the 2023 Michael E. DeBakey Excellence in Research award! Thanks to @PaulPfaffinger, Chair of @bcm_neurosci, for the support! The medal is bigger than the Nobel Prize Medal😀!
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Excited to see our new #voltageimaging paper in @NatureComms! @HelenXiaoyuLu, with @MXGHarryLiu & @GouYueyang , developed the #GEVI JEDI-1P. Dieter Jaeger, and @YunmiaoWang in his lab @EmoryUniversity, applied JEDI-1P for rapid widefield voltage imaging. rdcu.be/doqi2
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Finished teaching neuroscience methods in to our talented 1st-year grad students at @bcm_neurosci! Pictures show lab members teaching microscopy and data analysis. Big thanks to my fellow course instructors: @SynapsesInSight, @MattRasband, @AreyLab, and Elizabeth Zuniga-Sanchez.
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We have some beautiful state parts around Houston! Yesterday, several lab members and I hiked and enjoyed the wildlife and vegetation at Brazos Bend State Park. Recovered lost calories at a picnic by eating BBQ chicken and asparagus expertly cooked by postdoc Alex McDonald!
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We received a seed grant from the Genetic Design and Engineering Center (GDEC, gdec.rice.edu/) @RiceUniversity! GDEC will automate the development of large DNA libraries for a @CPRITTexas project. Excited to collaborate with Director Prof. Bao and Manager Dr. Gardner!
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New cool kid on the block: our bright and photostable yellow fluorescent protein mGold has earned an orange flame on @Addgene, indicating its popularity! addgene.org/157996/
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From last Saturday: eating crawfish and Asian food at my home with lab members, and their families & friends! We celebrated Harry's commencement earlier that day and Xiaoyu being awarded an @RiceSSPB research award last week.
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Attended the commencement of Dr. Zhuohe "Harry" Liu of @RiceECE who conducted his thesis work in my lab. Congrats, Harry!
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Congratulations to Xiaoyu "Helen" Lu, a graduate student in my lab, for receiving the @RiceSSPB Research Award for her outstanding publication record, including her 2022 voltage imaging paper in Cell! #GEVIs doi.org/10.1016/j.cell.2022.…
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Attending the keynote from Matthew Botvinik from @google @DeepMind: "AI as a window on brain function", as part of the McNair symposium.
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Postdoctoral fellow Dr. Michelle Land is presenting a poster on new biosensors (#GEVIs) to monitor neural activity. We're excited to be participating in the McNair symposium and grateful for support from the McNair Foundation!
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Upcoming lecture of Dr. Francois St-Pierre, the Department of Neuroscience at Baylor College of Medicine
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At the @RODEOHOUSTON in the Founder's Suite, courtesy of Mrs. Janice McNair, whose family is funding research in my lab and the groups of other McNair scholars. Thrilling performance by the @zacbrownband. Thank you for this invitation and your support of my research program!
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A wonderful time at the Winter Celebration of the St-Pierre lab with current and previous members! What a great team!!!
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Congrats to @JihwanJamesLee and @MXGHarryLiu in my lab for graduating from @NSF's #iCorps program! Due to Harry and James' efforts, our team received the "Pacesetter" award for landing the largest number of interviews (150!) from the whole cohort!
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Shuyuan Yang, a talented @RiceEngineering grad student working in my lab, presented an exciting poster on her work developing genetically encoded voltage indicators at the 28th Annual Neuroscience Poster session in Houston.
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Congrats to Dr. Michelle Land, a talented postdoc in my lab, for receiving a travel award to ACSB! She presented her work on novel genetically encoded voltage indicators last weekend! #CellBio2022 #GEVIs.
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Our poster on Genetically Encoded Voltage Indicators (#496.12/YY27) is being presented #SfN22 by @Helenxiaoyu (right) and @MXGHarryLiu (left). Great collaborative work on 1P imaging with the Jaeger lab. Bonus (red section) section of 2P imaging with @DieudonneLab.
Return of the JEDI! Padawan @HelenXiaoyuLu in my lab at @bcm_neurosci is presenting a poster on JEDI-1P and JEDI-2P, genetically encoded voltage indicators for 1P and 2P imaging, respectively. Nov15 morning, #496.12/YY27, in a galaxy not far away. #GEVIs #SFN
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Belated Happy Halloween from the St-Pierre lab! We had a Star Wars theme given our recent papers on JEDI voltage indicators. There was also a banana (I must have missed that episode!). See: doi.org/10.1016/j.cell.2022.… and biorxiv.org/content/10.1101/….
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Congratulations to Dr. Liu for successfully passing his PhD thesis defense! One picture shows Harry visibly relieved at the end of his presentation! Harry helped develop the JEDI series of #GEVIs, with the cake highlighting his transition from a Padawan to a JEDI master!
Harry Liu, a talented @RiceECE grad student working in my lab @bcm_neurosci, will be defending tomorrow (Monday) at 4pm! Please join his talk entitled "Multimodal High-Content Optimization of Neural Activity Biosensors" at Duncan Hall DCH 3092 or via Zoom: riceuniversity.zoom.us/j/962…
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Harry Liu, a talented @RiceECE grad student working in my lab @bcm_neurosci, will be defending tomorrow (Monday) at 4pm! Please join his talk entitled "Multimodal High-Content Optimization of Neural Activity Biosensors" at Duncan Hall DCH 3092 or via Zoom: riceuniversity.zoom.us/j/962…
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It's #PostdocAppreciationWeek! Just thanked my talented and dedicated postdocs on @bcmhouston's kudo board: kudoboard.com/boards/4XMLzbK….
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@RiceSSPB grad student @HelenXiaoyuLu led the epic protein engineering work in my lab @bcm_neurosci with teammates @MXGHarryLiu and @GouYueyang. Beautiful pan-cortical imaging by @Miaowater, a graduate student in the lab of co-corresponding author Dieter Jaeger @EmoryUniversity.
ALT Xiaoyu "Helen" Lu (left) and Francois St-Pierre (right)
ALT Yunmiao Wang (left) and Dieter Jaeger (right)
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JEDI-2P is now available as AAVs from @Addgene as double floxed soma-localized (addgene.org/179459/) and non-soma-localized variants (addgene.org/179460/). Enjoy! #GEVI
We finally achieved a dream I had 10 years ago: sustained (>30 min) deep-tissue (>400 um deep) imaging of fast voltage dynamics (e.g., spikes in bursts) in the brains of awake behaving mice. See our paper in *Cell* here: doi.org/10.1016/j.cell.2022.…
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Here are Yueyang "Eric", Zhuohe "Harry", and Xiaoyu "Helen" (left to right), the three protein engineers who developed JEDI-2P along with a stack of screening plates used to screen our voltage indicators thus far. #GEVIs #hardwork #go96wellplates
I want to thank Zhuohe "Harry" Liu from @RiceECE, Xiaoyu "Helen" Lu @RiceSSPB and @GouYueyang from @bcm_neurosci. They are co-first authors and worked in my lab to develop the two-photon screening system, and engineer and conduct detailed in vitro characterization of JEDI-2P.
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I'm tweeting several days late as I was on an anniversary/birthday Caribbean cruise. I did take a moment on August 18 to celebrate our publication!
We finally achieved a dream I had 10 years ago: sustained (>30 min) deep-tissue (>400 um deep) imaging of fast voltage dynamics (e.g., spikes in bursts) in the brains of awake behaving mice. See our paper in *Cell* here: doi.org/10.1016/j.cell.2022.…
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We got a visit from lab alum Jack Ahrens! Jack was an undergrad from Rice U. In our lab, he worked on developing the photostable fluorescent protein #mGold using #SPOTlightScreening, see doi.org/10.1126/sciadv.abb74…. He just joined Chad Mirkin's lab @NorthwesternU as a grad student!
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We're happy to welcome Dr. Matthew Shorey (pictured to the left) as a new postdoc in the St-Pierre lab @bcm_neurosci! Matt is hailing from the lab of Dr. Melissa Rolls at @PennState, where he studied the cytoskeleton and regeneration in flies and fish.
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Andre "Dre" Kirunda, first-year grad student @bcm_neurosci, finished his 2-month rotation in my lab engineering voltage indicators for imaging brain activity. BCM grad students conduct 3-4 rotations to find the "right fit". Dre was outstanding -- he's a Dr. Dre in the making!
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