Scientist of Living Matter, Professor @icreacommunity, Group Leader @ibecbarcelona, Jazz trombone @lalocojazz. The need to know.

Barcelona, Spain
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). @IBECBarcelona
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Xavier Trepat retweeted
Manuel Salmeron, director of #IBEC, has received the George Winter Award 2026 from the European Society for Biomaterials — its highest individual honour — for his research on biomaterials and mechanobiology for regenerative medicine. #ESB2026 👉More: ibecbarcelona.eu/manuel-salm…
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Xavier Trepat retweeted
What if we stop asking only how cells build tissues and ask how tissues shape cells? That’s what we’ll explore at Modelling Life from Tissues to Cells 🇨🇭 lakeconferences.org/conf/833…
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When tension increases the nucleus is compressed and escapes its keratin cage. New paper our in @NaturePhysics. Led by Tom Golde with theory by Marco Pensalfini and Marino Arroyo. nature.com/articles/s41567-0…
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Our latest work on shape-programmable tissues is out in @ScienceMagazine. science.org/doi/10.1126/scie… Collab with Marino Arroyo’s lab, led by @pauguillamat at @IBECBarcelona
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Less than a week to submit your abstract for #EESMechanobiology. Mechanobiology across the tree of life, from HeLa cells to weird animals and plants. The submission deadline is 3 March: s.embl.org/ees26-06-bl 🗓️ 9 – 12 June 2026
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📢 New extended abstract submission deadline: 6 January 2026! Outstanding speaker list, plus many slots for short talks by students, postdocs, and junior PIs. Join us in March in Barcelona! events.ibecbarcelona.eu/embl…
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📣Announcing the 4th edition of the EMBL‑IBEC Conference on “Engineering Multicellular Systems”, taking place 11–13 March 2026 in Barcelona. Exploring organoids, mechanobiology, embryo models, organ-on-chip systems, multiomics and more. Abstracts open now! events.ibecbarcelona.eu/embl…
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Xavier Trepat retweeted
Jochen Guck just passed away. He was not only a brilliant mind, amazing researcher, and outstanding person — he was also one of the best friends one could ever have. Jochen, you will be missed so deeply. Your spirit and laughter will stay in our hearts forever.
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New preprint! 🚨 We uncover a slow adaptation to stretch that links star-bundling of keratin filaments with nuclear escape from its keratin cage. Led by @tom_golde 🙌 @IBECBarcelona biorxiv.org/content/10.1101/…
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These topological transitions provide epithelia with a multiscale mechanism to adapt to sustained stretch. Beautifully modelled by Marco Pensalfini and Marino Arroyo.
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We are super excited to announce our Feb 2026 conference on the "Collectivity of living systems", bringing together the broad community studying biological collectives, covering their emergence, functionality and evolution! Please RT and join!!! embl.org/about/info/course-a…
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A thread of our new preprint 🧵👇 🤩
Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025.06.30.6… 🧵with pressure control, multiscale buckling, patterned wrinkling
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🚨 Second preprint of the week! We uncover the multiscale dynamics of active viscoelastic buckling in epithelia. We harness these mechanical instabilities for synthetic morphogenesis. Led by @onenimesa🙌. Theory by Marino Arroyo and team. biorxiv.org/content/10.1101/…
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How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by @pauguillamat @IBECBarcelona biorxiv.org/content/10.1101/…
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Xavier Trepat retweeted
There’s tons out there about fibroblast #mechanobiology in disease. In @ConfinementLab’s new review in @aplbioeng, Yeji gives you the who/what/where/when/how/why of mechanosensitive fibroblast activation, from CAFs to FAFs and nearly everything in between! pubs.aip.org/aip/apb/article…
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(6/6) In summary, our new pipeline now allows us to dissect how such a complex multicellular system like a budding intestinal organoid achieves its mechanical stability. Congrats to our shared first authors Oliver and Kim for this amazing work biorxiv.org/content/10.1101/…
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Xavier Trepat retweeted
1/7: New paper alert! Excited to share our co-first author paper on Micro Immune Response On-chip (MIRO) a model that recreates the tumour-stroma interface for immunotherapy testing! @Oriol_MB and I wrote this thread to break it down for you. 👇🧵 More: shorturl.at/evTKS
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