Proudly Melburnian, fuelled by coffee, dabbling in music & 3D printing. Now in NYC, Postdoc @asrc_gc: allostery in human PTPs w/ #xrays & #xtals. Views my own.
New York City
- Tweets 88
- Following 281
- Followers 134
- Likes 753
Blake Riley retweeted
Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
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Great to see former colleagues @DanielKeedy, Liliana & @DrAliEbrahim connect-the-(diffraction)-dots I left behind in my postdoc! Congrats to LG on her first 1st auth too!
New #keedylab #preprint! How does a protein structure differ at physiological temp vs. high pressure (vs. traditional cryo temp)? Liliana Guerrero (Margent) & @DrAliEbrahim looked into it: doi.org/10.1101/2023.05.02.5… Great collab w/ Qingqiu Huang & Aaron Finke at @MacCHESSCornell !
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Blake Riley retweeted
The Keedy lab at the @asrc_gc is seeking a computational #postdoc! Lots of exciting project directions linking protein structure, dynamics, allostery, bioinformatics, design, ... We're well funded, & are in a green pocket of NYC. Apply here: rfcuny.org/careers/postings?… RTs welcome!
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Blake Riley retweeted
If you’ve not had 11:12am in your local time yet today: get ready for the palindrific 2021-11-22-11:12:02
The rest of us can wait for 11 December.
@standupmaths Hi Matt, I have a life-long interest in date curios & I've just seen today's ISO date+time palindrome 2021112211202 - I notice the next one is 20211211211202, which if you lop the century & seconds off is 2112112112, ty
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Big fan of the Gemmi toolkit for #xtallography (@ccp4_mx / GΦL), and its cif & mtz command-line tools.
Now also available via : 💻 `brew tap brewsci/bio; brew install gemmi`
👏 @MacHomebrew & @brew_sci
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Blake Riley retweeted
Are you interested in discovering news ways to combat antimicrobial resistance? We have an exciting opportunity for an early career molecular microbiologist to join our multidisciplinary team. See details here and please feel free to share!
careers.pageuppeople.com/513…
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I don't think I've ever seen a more perfect coffee mug! Thanks Eta!
ALT Coffee mug, labelled "Fueled by Crystals & Coffee"
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Blake Riley retweeted
My research institute in NYC is looking for a talented scientist to join our team as research faculty (open rank)/ director of our Biomolecular NMR Spectroscopy Core Facility! DM me for more info, apply here: bit.ly/3wTJ3Lp
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Blake Riley retweeted
Our new preprint on multitemperature crystallography of SARS-CoV-2 Mpro is out! biorxiv.org/content/10.1101/… @DrAliEbrahim & @blake_riley took a detailed look at how Mpro reacts to being cooled/heated. We hope this helps ongoing antiviral design efforts (e.g. by @covid_moonshot).
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Done! A 49 hour beamtime at @CHESS_user with @DanielKeedy lab through both fall back and 🎃 Halloween. Hoping we see some ghostly density in our data #allostery #SpookyActionAtADistance 👻💎🤞
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ALT A 2 μL droplet, viewed through a microscope, which contains tens of well-defined protein crystals. Birefringence and a polarized light source casts an aesthetic rainbow effect across the entire image.
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Blake Riley retweeted
This is so amazing. So much fantastic structural biology and biophysics done in so short time!
Reminder to our politicians: This has only been possible because ALL the methods and instruments had been developed and ALL the people had been trained BEFORE the pandemic!!
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Room-temp diffraction @BrookhavenLab
#NSLSII
Me: "Just hold still so I can blast you with my million-sun x-ray beam!"
Crystal: "Wheeeeeeeeeeeee!"
(Crystal is ~2 hairwidths long).
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Blake Riley retweeted
This is simple, clear, clever, and informational. Salute @washingtonpost. Share with that friend who insists on hitting the town tonight. #StayHome washingtonpost.com/graphics/…
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Blake Riley retweeted
"By refusing to use the titles scientists have earned, news outlets contribute to the delegitimization of expertise." – @NPR's editorial policy is completely inconsistent with their mission to inform and educate the public. #CallMeDoctor blogs.scientificamerican.com…
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Blake Riley retweeted
“a perpetual financing machine”
Scientific publishing is a rip-off. We fund the research – it should be free.
theguardian.com/commentisfre…
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Blake Riley retweeted
Thoroughly enjoyed the first training with the BDI footy team tonight - this squad is going to bring some competition to the field! 💪🏽 @MonashBDI @MonashUni
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