How do you manage immunosuppression in dialysis-dependent glomerulonephritis?
🛑STOP: When risks outweigh benefits (e.g., infections, malignancy, fatal drug interactions). Primum non nocere.
⤵️TAPER: When renal recovery is unlikely (e.g., extensive IF/TA or advanced irreversible Anti-GBM injury), or to prevent rebound complications (e.g., prolonged corticosteroid therapy).
✅CONTINUE: If renal recovery remains possible, extrarenal disease is active, or to reduce post-transplant recurrence risk in selected active diseases.
Special thanks to 18th ADC Conference Leadership for the Kind Invitation.