Congrats to all the STOP-COVID Investigators on this important work!
Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19 ja.ma/3kicqRF via @JAMAInternalMed part of @JAMANetwork
Among adults with tumour lysis syndrome, early rasburicase treatment was associated with about one third lower risk of acute kidney injury requiring kidney replacement therapy or death compared with delayed or no rasburicase treatment, finds new BMJ study
bmj.com/content/394/bmj-2026…
Super excited to share that our paper on rasburicase for tumor lysis syndrome is now out in @bmj_latest. Using target trial emulation and data from 36 U.S. sites, we found a major mortality benefit with early rasburicase. bmj.com/content/394/bmj-2026…
New publication from our Onconephrology group on eGFR discordance and its impact on HSCT and adoptive T-cell therapy.
bit.ly/4tzNfxC@Api_chew@ShrutiGkidney
Excited to share our study on RBC exchange transfusion in severe babesiosis, now in @JAMAInternalMed. With Peter Krause and collaborators across 82 hospitals, we found substantially improved clinical outcomes in severe disease.
jamanetwork.com/journals/jam…
Congratulations to David Leaf @DavidLeaf9 and Leonardo Riella @LVRiella for election into the American Soc of Clinical Investigation @the_asci. They join M. Amin Arnaout, Jodie Babitt, Joseph Bonventre, Anna Greka, Herbert Lin, Eugene Rhee, Jing Zhou as MGB divison members
Does Vitamin D protect against kidney injury?
Here, @waikarss@DavidLeaf9 & team @BrighamWomens conduct a phase 2, randomized, double-blind, multi-dose, 3-arm clinical trial in critically ill adults. While treatment with calcifediol or calcitriol upregulated genes in several pathways and had anti-inflammatory effects, it did not prevent acute kidney injury: insight.jci.org/articles/vie…
Prophylactic IV magnesium administration was associated with a lower risk of cisplatin-associated acute kidney injury (CP-AKI) in patients with cancer undergoing cisplatin chemotherapy. ja.ma/4jKv4Qq
Most viewed this week from @JAMAOnc:
Prophylactic IV magnesium administration was associated with a lower risk of cisplatin-associated acute kidney injury (CP-AKI) in patients with cancer undergoing cisplatin chemotherapy.
ja.ma/44fFHqa
Happy Miracle on Ice Day if you’re observing it.
45 years ago today, February 22, 1980, a bunch of hard-nosed American college kids beat the seemingly invincible Soviets at 1980 Winter Olympics in Lake Placid, NY.
“Do you believe in miracles? Yes!”
Huge congrats to @ShrutiGkidney, @sarahkaunfer, and our many collaborators throughout the country on this achievement! Thrilled to see this in @BloodJournal.