Cell biology, genetics, biotechnology, algae & other green organisms; I study (and often torture) chloroplasts; group leader @GMIVienna @ViennaBiocenter.
GMI, Vienna Biocenter
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Vault proteins (aka “the sirens of cell biology”🧜♀️) are back in the headlines! But before we get carried away from the hype… Claude couldn’t crack their function, joining a long line of scientists lured into the mystery. Easy to spot, difficult to figure out…
Exclusive: Artificial intelligence has tackled a mystery that has flummoxed cell biologists for decades.
Today, Anthropic reports its key #AI model, Claude, has helped unearth new clues about vaults—strange, barrellike structures, found by the thousands in animal and plant cells, that still have no known function despite scores of studies.
In a blog post and related preprint, Anthropic describes how its small team of in-house biologists, guided by Claude, produced the first direct evidence that bacteria, viruses, and perhaps other simple microbes also make the odd structures.
Learn more: scim.ag/4eRMQRV
ALT AI company’s research deepens mystery of vaults, cells’ strangest particles Anthropic used its Claude AI to show bacteria and viruses also likely make the odd structures, suggesting an ancient origin
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"In the end, I have come to realize that being authentic at work is not a weakness, but rather a strength." #ScienceMagArchives scim.ag/44LmCvh
ALT An illustration of a woman wearing an axolotl costume in front of an audience, with the headline: Embracing my silly side makes me a better scientist. I wish I’d done it sooner
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Cysteine is essential for life, and toxic in excess. Cells keep its abundance tightly controlled despite constant inputs from diet and metabolism. How cells directly sense cysteine and prevent its accumulation has been a longstanding mystery that our new paper addresses:
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No words can express how I feel. Marta was one of the brightest lights in my scientific lineage - like a daughter. I love Marta because she was incredibly warm, generous, inspiring, a wonderful, thoughtful friend who I use as a role model for my students: “Be like Marta”.
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An engineered, compact Cas12m variant for multiplexed gene activation in vivo nature.com/articles/s41587-0…
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Literally #FoodForThought!
AI can write poetry, solve equations, and maybe even take over our jobs…
But as long as computers can't smell freshly baked bread, savor a perfect pasta, or fall in love with the aroma of good coffee, I’d argue humanity still has the upper hand 🙃
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Please help us spread the word! 📢
Our Institute is looking for a Scientific Director: oeawnr.onlyfy.jobs/de/job/u3…
Application deadline: November 15!
The @gmivienna is a truly exceptional place to do science and it is very generously funded by @oeaw ! 1/ 5
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A unique opportunity for an inspiring, progressive leader to build on these strengths and take GMI’s international visibility and prestige even further. 4/5
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The Structural History of Eukarya (SHE): The first proteome-scale phylogeny constructed entirely from 3D structure. We computed 300 trillion alignments across 1,542 species to map the tree of life. Now published!!! science.org/doi/10.1126/scia…
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Who knew amyloid (yes, as in Alzheimer's disease) makes deliveries of RNA to sperm for translation in the embryo?!
@MolecularCell
sciencedirect.com/science/ar…
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An inspiring speech by the Nobel Prize Serge Haroche at the @ESET Science Award Gala on AI as a powerful tool for scientific discovery, particularly when combined with uniquely human qualities such as emotion, intuition, and our sensory perception of the world ❣️
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A role model: Ruzena Bajcsy. Her speech at the ESET Science Award Gala is definitely worth listening to!
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Excited to share what we’ve been building with Chaperone!
In our benchmark, Chaperone reduced token usage by 86%. We also went from hypothesis to sequences ready for wet-lab testing in just two weeks—yielding a 1.32 nM cortisol binder in the first experimental round!
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Congratulations to Martina Legris @martina_legris, @FankhauserCh and the rest of the team for this exciting discovery 💚!
Plants don’t have eyes or brains. How do they know where light is coming from? Seedlings “see” with their whole bodies. quantamagazine.org/plants-fi…
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Plants don’t have eyes or brains. How do they know where light is coming from? Seedlings “see” with their whole bodies. quantamagazine.org/plants-fi…
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