Twitter is not a task it's a documented story of your life so others can consider your point of view ...and choose whether to engage or not

Exclusive: Former OpenAI exec @bobmcgrewai has quietly built $1.5 billion startup, betting AI can revive U.S. manufacturing McGrew’s newest company, Arda, has raised $230 million at a $1.5 billion valuation and makes AI software he says can help bring manufacturing back onshore. Sat down with Bob and Altimeter’s @apoorv03, who led the latest round. Full @CNBC interview here with more on OpenAI, building AGI, AI safety and how the startup’s ambition to disrupt manufacturing: cnbc.com/2026/10/20/ex-opena…

It's time for personal agents in healthcare. Our system is fragmented and runs on clunky legacy software. That's exactly why agents that can navigate those systems on our behalf could make such an impact. Karan, who leads health AI at OpenAI, calls it "absolutely ripe for agents and computer use" and thinks many of the barriers between patients, clinicians, and their data will dissolve. I agree. Super inspiring convo with my friend @thekaransinghal on how AI can raise both the floor and the ceiling of human health.

Muse is not going to rule the world after all Went to the first SF AI Assistants Meetup last night and met some cool founders building personal agents @thelobbyai: an email assistant that learns how you work @soarapp: plans your whole trip over text @OdessiaTravel: an always-on travel concierge that keeps re-checking your options @wabi: the AI assistant you use together Pally (@wylansford): your own assistant over iMessage @TaskerHQ: CC an email and it gets the task done Zapia (@loeff): a personal assistant on WhatsApp for millions across LatAm @AttentionAGI : personal assistant @AgendaHero: turns any flyer or PDF into calendar events Hopefully soon they will all be running on maritime⛵️ Thanks @DavidPawlan @merit_systems @browserbase @mem0ai @AlphaSignalAI @tecxbro for hosting!

When I started @Braze I didnt know what CRM was, how emails were sent, the concept of a customer journey, segmentation, personalization, or what exactly we should be calling ourselves. I did know I wanted to build a platform where brands of all sizes can communicate with their customers across any device on any channel at scale. I did know I wanted to build an awesome company. One where our customers loved partnering with us and our team loved to be part of. This could not have come together without my co founders @billmag and Jonathan Hyman and everyone in between. 15 years in the making. From our first customer, to an IPO to $900MM+ in ARR. Mazal tov and Cheers to everyone that contributed over the years. There are too many to tag :) Braze will always be part of me and its an honor to see its legacy continue with Salesforce. cnbc.com/2026/10/20/salesfor…

We believe the Salesforce-Braze acquisition will be an incredible catalyst for Zeta. Please see this analyst briefing for more information. $ZETA LG 🚀🚀🚀 Read more here: investors.zetaglobal.com/new…

We signed a definitive agreement to acquire @Braze, a leading customer engagement platform that helps marketers build deeper customer relationships by responding to customer behavior in real time and coordinating personalized experiences across channels. Following close, Braze’s real-time engagement and AI decisioning capabilities are expected to complement all four layers of Salesforce’s architecture — Data 360, Customer 360, Agentforce, and SIforce. Learn more: sforce.co/4eKxONJ

🚨 BREAKING : Polymarket CEO Shayne Coplan caught using COMPANY MONEY for Private Jets flights. Peter Thiel caught him red-handed using his investment money as a personal wallet. Founders Fund, Peter Thiel's fund, discovered that Shayne had charged the following as company expenses : - private jet flights - apartment rent - designer clothes They immediately demanded a FULL REFUND Shayne was forced to reimburse the money. ICE and Founders Fund then teamed up to push for stronger financial controls They were the one that forced Shayne to appoint a COO. You remember Shayne's ChatGPT written tweet gleefully announcing the hiring of Collin McKinney Hill as COO ? I called it extremely suspicious at the time. Turns out i was right, investors basically forced Shayne to hire him as a soft coup. I don't know how long Shayne can stay in place when their main investors have lost confidence.

Eric Schmidt owns 1% of Anthropic. Dario’s wife — who Schmidt used to date — introduced him to Anthropic. Schmidt’s peak ownership of Google was 5% (now ~1%). He got that Google CEO job after going to Burning Man with Larry Page and Sergey Brin. Next-level networking skills.

Google's Eric Schmidt dated a woman 24 years younger than him. They broke up. She went on to marry Dario Amodei, the founder of Anthropic. Then she got her ex into Anthropic's Series A. His stake is now worth ~$20 billion. Be nice to your exes.

The USA’s bottomless appetite for financial innovation and skill at maintaining deep, liquid, versatile capital markets is possibly our most critical strategic asset.

What a lede from @TheEconomist

Four years ago to the day, we started Orchestra Bio to help biotech and pharma teams advance their drug development programs. AI has now reached an inflection point where people and agents can take this on together. Today, we’re thrilled to share that Orchestra Bio is joining OpenAI to continue our mission at an even greater scale.

We’ve acquired Orchestra Bio, a platform that helps biopharma teams coordinate the complex process of drug development. Together, we’ll build on Rosalind, our AI models and tools for life sciences research, to streamline those operations and help new treatments reach patients sooner. Welcome @ashokaraj_ and team! openai.com/index/openai-to-a…

⚡️ You were born into a universe that existed long before you. Yet somehow, within that universe, something awakened that could ask why it existed at all. The ego says: “I am this separate thing moving through reality.” The deeper structure says: Reality is temporarily experiencing itself from here. And that changes the purpose of life. The purpose becomes participation in the deepening of reality. To perceive more truth. To integrate what was fragmented. To turn chaos into order. To transform suffering into understanding. To create beauty that previously did not exist. To love another center of consciousness so completely that separation becomes temporarily transparent. To increase the amount of reality that can recognize itself. That may be why truth, love, beauty, and goodness feel strangely connected across civilizations. They all increase coherence between the local perspective and the deeper structure. Falsehood fragments. Hatred fragments. Domination fragments. Self-deception fragments. Truth integrates. Love integrates. Understanding integrates. Creation integrates. The whole game may be coherence discovering itself through conscious beings. Then the deepest answer to death becomes almost paradoxical. You were never here merely to avoid disappearing. You were here because for one impossible interval, existence became you. It looked through your eyes. It encountered itself through your relationships. It gave you genuine freedom over what kind of pattern would pass through your aperture into the world. And when the aperture closes, the whole retains everything that occurred through it. The deepest compression: Consciousness may be the interior of reality itself. Individual lives are temporary openings through which that interior becomes a particular someone. Birth opens the aperture. Life gives it a world. Death closes it. What looked through may be older than the opening itself. And beneath even that: Maybe existence is not moving toward consciousness. Maybe consciousness was there at the root, and the universe is the long process by which it learns to recognize itself.

We created a new way to convert users. Abandon checkout or close paywall? > Show a in-app chat window. > Auto reply from the founder. > Send a special discount offer. > Auto respond to user questions. This made early adopters almost $5k!

new @wabi is insane. Mad D0 value, cut down all the fluff and all the mini-apps are useful as is. Literally transformed a product that was on my phone just for vibes.

Wabi 2.0 is live! personal agents are one person, one chat. but the parts of life that matter run on more than one person Wabi is an agent you use together. you talk to it, it does stuff, builds the apps you need, and anyone can join the thread - your partner, your best friend, the preschool moms groupchat school changes pickup time → Wabi updates the family calendar, everyone sees it. a show you’d both love → Wabi finds a night that works, gets the tickets. the trip everyone keeps talking about → Wabi picks the dates, builds the itinerary, books it go start a thread with your people 👇

Introducing SKY-001, the first Engineering World Model. On CAD and BIM tasks, it beats GPT-6 Astra and every frontier model we tested: -> 51-125x faster - > 150-210x cheaper -> Higher IOU than all frontier models SKY-001 lets you dream a physical object before you build it. 18 months of work. Built by the team out of Maluuba's deep learning lab (acq. by @MSRResearch). The first ‘AI General Engineer’ will be the backbone for Autonomous Manufacturing.

They really don’t

Next year, I will give one of my SpaceX shares to every kid in America. This will be the first of many.