#PancreaticCancer Research Lab interested in selective #autophagy, iron, therapeutic resistance, and #proteomics. @DanaFarber, @BrighamWomens, @harvardmed

Boston, MA
Congratulations to @SantanaCodina on your amazing time in the Mancias Lab! We are so lucky to have worked with you over the years on #PancreaticCancer biology and are pumped to see what your #NewPI adventure holds in store! Buen viaje and good luck Naiara!!
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The Mancias Lab and @GygiLab are hiring a co-mentored postdoctoral fellow. Join our teams to work on projects related to #PancreaticCancer and #Proteomics. Please apply via this link: tinyurl.com/y929vp54 DM if questions. Please RT! @DanaFarber_Hale @HarvardCellBio
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The Mancias Lab is hiring research technicians! Join our team to work on projects related to #PancreaticCancer #Autophagy and #Iron. To learn more about us, check out our website. Apply via the links, DM if questions. Please RT! social.icims.com/viewjob/pe1…  social.icims.com/viewjob/pe1…
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The Mancias Lab and @GygiLab are hiring a co-mentored postdoctoral fellow. Join our teams to work on projects related to #PancreaticCancer and #Proteomics. Check out the post below and DM or e-mail me if interested. Please RT! @DanaFarber_Hale @HarvardCellBio
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Thank you to @LyssiotisLab @YatrikShahLab for the invitation for a virtual visit to @UMPhysiology today to present our work on iron and autophagy metabolism in #PancreaticCancer - work led by the stellar @SantanaCodina in the lab. Great day chatting with everyone!
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Great day for the @DamonRunyon virtual @runyon5k for #CancerResearch. Thanks to @DamonRunyon for supporting #PancreaticCancer research in my lab and for all you do supporting science. Pics from my virtual run/walk this year in Boston and great memories from 2019 @yankeestadium!
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Goods news for the lab amidst these sad times: our study on mechanisms of adaptation to KRAS-G12C inhibitors in @CellReports. Congrats to co-firsts @SantanaCodina @amrita_singh89, thanks to collaborators: @andrewaguirremd Gray Lab @DFCI_ChemBio Fendler Lab. #tweetorial by Naiara:
Good news in these strange days!! Our paper is out @CellReports !! We have used quantitative temporal proteomics to define mechanisms of adaptation to KRASG12C inhibitors and to develop combinatorial regimens. Congrats @amrita_singh89 @ManciasLab! cell.com/cell-reports/fullte…
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Pics from our Annual Mancias Lab Holiday Party: another great year in the books! Grateful for our lab members and all their hard work! @RosebudKitchen @UrbanAxes (Watch out #PancreaticCancer #MiljanTheAxeWielder is coming for you!) #UglyChristmasSweater
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Congratulations to Dipanjan Chowdhury ⁦@ChowdhuryLab⁩ ⁦@DanaFarber⁩ #RadiationOncology for his promotion to full professor ⁦@harvardmed⁩ !
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to enhance response to KRASG12C monotherapy. Combinations with CDK4/6i and HSP90i showed promise but would require further extensive pre-clinical testing to validate. All of our quantitative temporal proteomic data is available via an interactive website: manciaslab.shinyapps.io/KRAS….
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KRASG12C inhibitors are now in clinical trials for oncogenic KRASG12C-driven tumors including in #LungCancer and patients are showing responses. As one concern based on experience with other targeted therapies is development of resistance, we modeled adaptation/resistance
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Naiara Santana-Codina presents work from the lab at #AACRPanCA19 on using quantitative temporal proteomics to identify combinatorial treatment strategies in #PancreaticCancer, great work Naiara @SantanaCodina! @HaleCenter_DFCI
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Annual summer lab bbq was a success! I’m grateful for all the lab members and their hard work figuring out #pancreaticcancer #ironmetabolism #autophagy. @DanaFarber
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Lab outing to celebrate submission of latest grant! Fingers crossed! ⁦@EventideFenway⁩ ⁦@veapen1⁩ ⁦@naiara_nsc⁩ #pancreaticcancer
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Joint #GujarLab @ManciasLab ⁦@RedSox⁩ game outing ahead of our joint lab meeting on #immunopeptidome workshop relevant to #pancreaticcancer ⁦@pitter9⁩ ⁦@naiara_nsc⁩ ⁦@labratprats⁩ ⁦@veapen1⁩ ⁦@DanaFarber⁩ ⁦@DalhousieU⁩ ⁦
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Awesome #EMBLBioIron conference this last week with great presentations/posters including on role of iron metabolism in cancer and ferroptosis. Great catching up with collaborators including ⁦@YatrikShahLab⁩ ⁦@suzcloo⁩
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#TBT to last week: our first annual lab BBQ! Honored to work with this amazing group of people on #PancreaticCancer @DanaFarber
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#TBT to last week: our first annual lab BBQ! Honored to work with this amazing group of people on #PancreaticCancer @DanaFarber
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Our work today in @NatureComms Compensatory networks in #PancreaticCancer upon perturbation of glutamine metabolism nature.com/articles/ncomms15…
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