Medical Oncologist, department of oncology at the University hospital of Geneva (HUG). All opinions expressed here are my own

Genève, Suisse
Alfredo Addeo MD retweeted
Delighted to share this new paper in the European Journal of Cancer: radical local treatment for NSCLC patients with oligoprogression after chemoradiation and durvalumab. 🫁 doi.org/10.1016/j.ejca.2026.…
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Alfredo Addeo MD retweeted
Can T-cell engagers create a "tail of the curve" phenomenon in #SCLC, in a way similar to ICIs? Apparently yes! Long-term Follow-up (22m) of the Dellphi-304 trial as published in @Annals_Oncology and reported in #ESMO2026 by @charlesrudin show 30% pts alive at 2 yrs with tarla compared to 15% with chemo. Sustained disease control for ≥52 weeks was observed in 24.4% versus 4.3%. Confirmatory results of prolonged tarla efficacy, giving hope to our patients @SclcSMASHERS @SCLCYIForum @LungCancerEu @YoungLungCancer @myESMO @IASLC @ASCO annalsofoncology.org/article…
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Alfredo Addeo MD retweeted
Great guest post by @sarojniraula, discussing his recent @JCO_ASCO editorial with Ian Tannock! @TheWonkologist et al. showed that payments as small as $45 are associated with prescribing decisions involving anticancer drugs. And these drugs can cost tens of thousands of dollars per month! Post here: theoncologyshot.com/p/curren…
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Alfredo Addeo MD retweeted
#ESMO26: Phase III OptiTROP-Lung06 #ClinicalTrial reports a game-changing 51% reduction in the risk of progression or death with the #ADC sacituzumab tirumotecan added to pembrolizumab in advanced #NSCLC ➡️ ow.ly/QYUT5102qlv #InsightsbyESMO @g_mountzios
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Alfredo Addeo MD retweeted
Inspired by Science, United by One Goal at ESMO 2026 - Alfredo Addeo @Alfdoc2 oncodaily.com/community/alfr…
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Alfredo Addeo MD retweeted
Always enjoy discussing the latest data with @high5md - this session on the biggest impact data from #ESMO26, gaining perspectives from Drs. @Griesinger35711 @Alfdoc2 @HendriksLizza @nicogirardcurie @DMSLung @DrRiyazShah @MartinReck2 high5oncology.tv/meeting-cov…
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Alfredo Addeo MD retweeted
Practice Changing...Or Not? 👉OptiTROP-Lung04 #ESMO26 ✅ New SOC?: “Impressive FINAL OS results from OptiTROP-Lung04 at #ESMO26!” @Alfdoc2 ❌ Or not?: “Global validation and treatment-sequencing questions remain.” @Latinamd KOL Reactions: Practice Changing…Or NOT — 10 ESMO26 Controversies Oncologists Debated on X hubs.ly/Q04CS7qL0
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Alfredo Addeo MD retweeted
Friends, 🙏 consider voting for @RManochakian who has been a phenomenal educator, clinician and patient advocate! I remember meeting him when I came to @MayoCancerCare FL and his warm and kind personality stayed with me since! @ASCO will be lucky to have him join!
#Voting for @ASCO Election is now open. I am #honored & #humbled to be running as one of the candidates, for the #ASCO #NominatingCommittee, alongside many remarkable talented candidates & GREAT colleagues.   Visit asco.org/election to learn more about the candidates & place your vote!
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Sometimes important studies fly under the radar and I was rather surprised to see hom many collegue knew the TRIPLEX trial (not yet fully published but not ours, fully published) TheSAKK 15/19 trial phase II trial in ES-SCLC missed its 12-month PFS endpoint but showed encouraging safety with TRT AFTER chemo-IO induction and quite long OS (> 16 months mOS) In contrast, TRIPLEX (#ASCO26) raised major safety concerns with concurrent TRT. Is TIMING the key? And what about TRT in the T-cell engager era? Efficacy remains uncertain, but perhaps the question is not just WHETHER to irradiate, but WHEN @sands_jacob @AndrearicFili @StephenVLiu @DrewMoghanaki 🔗 ejcancer.com/article/S0959-8… #SCLC #LungCancer
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Alfredo Addeo MD retweeted
📣 Registration for #ELCC27 is now open. Join a focused, multidisciplinary thoracic oncology community to discuss the latest research, exchange perspectives and connect with colleagues from across the field. 🔗 Register now: ow.ly/sglQ50ZZctT #esmomeetings
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The M2 metro from Lausanne station stops at CHUV, a short walk from the Agora building, Rue du Bugnon 25A. That is where the International Lung Cancer Summit (ILCS) 2026 meets on 13 November, from 09:45 CET, with every talk also live online. We look forward to welcoming you at the door. ILCS 2026 faculty: @peters_solange @Alfdoc2 @DasMillie11 @HHorinouchi @TelmaSequeiraMD @christine_lovly @dplanchard @PatelOncology @ACortelliniMD @g_mountzios @a_dingemans Registration is open: lungsummit.org/registration/ #ILCS2026 #LungCancer #NSCLC #SCLC
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Alfredo Addeo MD retweeted
#Voting for @ASCO Election is now open. I am #honored & #humbled to be running as one of the candidates, for the #ASCO #NominatingCommittee, alongside many remarkable talented candidates & GREAT colleagues.   Visit asco.org/election to learn more about the candidates & place your vote!
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Fascinating presentation at the HUG Research Day 2026! @hug_ge Augmented reality meets paediatric resuscitation! The InterFACE-AR study explored how augmented reality can support clinical teams during paediatric cardiac arrest, improving coordination and adherence to resuscitation protocols. Promising results from a randomized simulation study, with fewer adrenaline doses administered outside the recommended time window. Well done to the research team! Great to see @hug_ge pushing the boundaries of innovation and translating technology into potentially better patient care! jamanetwork.com/journals/jam…
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Alfredo Addeo MD retweeted
You have my vote 🗳️@RManochakian @MayoClinic for @ASCO Nominating Committee 👇
#Voting for @ASCO Election is now open. I am #honored & #humbled to be running as one of the candidates, for the #ASCO #NominatingCommittee, alongside many remarkable talented candidates & GREAT colleagues.   Visit asco.org/election to learn more about the candidates & place your vote!
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Alfredo Addeo MD retweeted
More thoracic voices on SAFFRON — are you testing for MET overexpression/amplification at osimertinib progression, and how do you weigh OS HR 0.68 against fatal AEs 7% vs 0% while savolitinib remains investigational in the US? @JhanelleGray @DrRoyHerbst @AnaVManana @DrRaviSalgia @LovaSunMD @drtahuahua @ManuelDomine @peters_solange @Alfdoc2 @g_mountzios @TommyJohn00 @DevikaDasMD @HerediaOncologo @ShirishGadgeel @DrJNaidoo @cpeedell
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Alfredo Addeo MD retweeted
More thoracic voices on Krascendo-1 — how are you counseling pretreated KRAS G12C NSCLC when divarasib remains investigational and approved G12C inhibitors stay the labeled options? @JhanelleGray @DrRoyHerbst @AnaVManana @DrRaviSalgia @LovaSunMD @drtahuahua @ManuelDomine @peters_solange @Alfdoc2 @g_mountzios @tnewsomdavis @TommyJohn00 @DevikaDasMD @HerediaOncologo @DavidHongMD
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I couldn’t think of anytime better tbh
#Voting for @ASCO Election is now open. I am #honored & #humbled to be running as one of the candidates, for the #ASCO #NominatingCommittee, alongside many remarkable talented candidates & GREAT colleagues.   Visit asco.org/election to learn more about the candidates & place your vote!
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